Name | Isopropyl palmitate |
Synonyms | IPP kesscoipp Lexol IPP nikkolipp plymouthipp Liponate IPP Plymouth ipp Isopropyl palmitate Palmitic acid esters kesscoisopropylpalmitate propan-2-yl hexadecanoate Palmitic acid isopropyl ester Hexadecanoic acid isopropyl ester |
CAS | 142-91-6 |
EINECS | 205-571-1 |
InChI | InChI=1/C19H38O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19(20)21-18(2)3/h18H,4-17H2,1-3H3 |
InChIKey | XUGNVMKQXJXZCD-UHFFFAOYSA-N |
Molecular Formula | C19H38O2 |
Molar Mass | 298.5 |
Density | 0.852 g/mL at 25 °C (lit.) |
Melting Point | 11-13 °C (lit.) |
Boling Point | 160°C 2mm |
Flash Point | >230°F |
Water Solubility | Not miscible or difficult to mix with water. |
Vapor Presure | 0.007Pa at 25℃ |
Appearance | neat |
Color | Colourless |
BRN | 1786567 |
Storage Condition | 2-8°C |
Refractive Index | n20/D 1.438(lit.) |
Physical and Chemical Properties | Density 0.852 refractive index 1.438 flash point> 110°C |
Use | Widely used in the pharmaceutical industry and cosmetics industry |
Hazard Symbols | Xi - Irritant |
Risk Codes | R36/38 - Irritating to eyes and skin. R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | - |
RTECS | RT4900000 |
TSCA | Yes |
HS Code | 29157090 |
Raw Materials | Isopropanol Palmitic acid |
LogP | 8.16 |
NIST chemical information | Information provided by: webbook.nist.gov (external link) |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
overview | isopropyl palmitate is a traditional, refreshing, fast-spreading emollient for modern cosmetics. As the main carrier or conditioning ingredient in a wide range of cosmetic applications. Its performance: stable, not easy to oxidize or produce peculiar smell, can make the skin soft without greasy feeling, is an excellent skin softener. Isopropyl palmitate is a small molecule oil with small molecular weight, which can penetrate into the epidermis to prevent evaporation of water, moisturize the skin, and improve symptoms such as dryness and water shortage. But at the same time, it will also penetrate keratinocytes, and excessive use will cause the skin to keratinize and become rough and sallow. And some experiments have shown that isopropyl palmitate will promote the reproduction of Malassezia, and the excessive reproduction of Malassezia may lead to fungal acne, which is why some people use powder water to grow acne. |
application in cosmetics industry | this product is widely used in cosmetics and has excellent moisturizing and moisturizing effects on skin. The skin has a good absorption of this product. It can effectively contact with hair follicles in the cortex, penetrate into the depths of the cortex, and bring in the active components in cosmetics to give full play to the role of active ingredients. As a cosmetic solvent and skin moisturizer, penetrant, isopropyl palmitate can be used in sol products, bath oil, hair conditioner, skin cream, sunscreen, shaving cream and other cosmetics. The addition amount of this product in cosmetics is 2-10%. |
use | used in cream, lipstick, facial cleanser and bath lotion. after use, the cream is delicate, bright and free of greasy feeling. Widely used in pharmaceutical industry and cosmetics industry |
production method | add 1 mol of decanoic acid to the reaction kettle, add 1.5 mol of isopropanol, stir and dissolve, add the amount of sulfuric acid with the catalyst, reflux under stirring for 10 h, and evaporate excess isopropanol and water. Cool, add 5% Na2CO3 aqueous solution to neutralize, separate the water layer, and dehydrate the product under reduced pressure. |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |