Polyphyllin F (Polyphyllin VI)
Polyphyllin VI
CAS: 55916-51-3
Molecular Formula: C39H62O13
Polyphyllin F (Polyphyllin VI) - Names and Identifiers
| Name | Polyphyllin VI |
| Synonyms | Polyhyllin VI Polyphyllin Ⅵ Polyphyllin VI Paris saponin VI 17-Hydroxyparis V Chonglou saponin Ⅵ Polyphyllin F (Polyphyllin VI) (2R,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-4,5-Dihydroxy-2-(((2'R,4S,5'R,6aR,6bS,8aS,8bS,9S,11aS,12 |
| CAS | 55916-51-3 |
Polyphyllin F (Polyphyllin VI) - Physico-chemical Properties
| Molecular Formula | C39H62O13 |
| Molar Mass | 738.9 |
| Density | 1.38 |
| Melting Point | 216-220°C |
| Boling Point | 871.2±65.0 °C(Predicted) |
| Specific Rotation(α) | -117.8 (Py) |
| Solubility | Soluble in methanol and water |
| Appearance | White crystal |
| Color | White to Off-White |
| pKa | 12.85±0.70(Predicted) |
| Storage Condition | Hygroscopic, Refrigerator, under inert atmosphere |
| MDL | MFCD13195303 |
| Physical and Chemical Properties | White crystalline powder, easily soluble in methanol and water, derived from heavy buildings. |
Polyphyllin F (Polyphyllin VI) - Reference
| Reference Show more | 1. Xiang Yan, Yin Ling, Yang Linhui. Effects of polyphylla saponin VI on invasion and migration of human colon cancer cells [J]. Journal of Gastroenterology and Hepatology, 29, 28, 12,, pp. 2019-1402. 2. Liu Jia, Yang Yali, Zhang Peng, et al. Analysis of the content of saponins in different parts of 4 kinds of Paris polyphylla [J]. Chinese Journal of Experimental formulology, 2016, Vol. 22, 16, pages 44-48. 3. Wang Haiming, et al. Determination of four saponins in Rhizoma Paridis by HPLC [J]. Journal of Dalian Minzu University, 2018, 20(001):17-20. 4. Ye Feifei, Xu Haobo, Wang Chunxia, et al. Simultaneous determination and cluster analysis of four saponins from Paris polyphylla [J]. Chinese patent medicine 2016 38(11):2413-2413. 5. Liu Jia, Zhang Peng, Song Fa-Jun, etc. Analysis of the content of four kinds of saponins in the ground part of Paris polyphylla [J]. Shi Zhen, National Medicine, 2015, 026(005):1233-1235. 6. Liu Xiaofen, Huang Xiaozhi, He-Shan Wang. Quality Evaluation and Analysis of cultivated Paridis in Fujian province [J]. Fujian Traditional Chinese Medicine, 2012, 43(005):53-55. 7. Liu Xiaofen, Yang Chengzi, Huang Zehao, etc. Characteristics of Rhizoma Paridis and content analysis of four saponins [J]. Fujian Traditional Chinese Medicine, 2014, 045(001):53-56. 8. Wang Shibao, Cai Yanni, Jia Huimei et al. Determination of seven steroidal saponins in Rhizoma Paridis from different sources by HPLC [J]. Northwest Pharmaceutical Journal, 2017, 32(002):133-138. 9. Wang Shibao, Su Ying, Li Huining et al. Optimization of reflux extraction of steroidal saponins from Rhizoma Paridis by response surface methodology [J]. Shaanxi Agricultural Sciences 2019 065(001):46-52. 10. Liu, Feng, et al. "Comparative analysis of proteinic and metabolic profiles of different species of Paris." Journal of proteomics 200 (2019): 11-27.https://doi.org/10.1016/j.jprot.2019.02.003 11. Liu, Feng, et al. "Comparative analysis of proteomic and metabolomic profiles of different species of Paris." Journal of proteomics 200 (2019): 11-27.https://doi.org/10.1016/j.jprot.2019.02.003 12. [IF=4.072] Yan Yin et al."A cytochrome P450 monooxygenase responsible for the C- 22 hydroxylation step in the Paris polyphylla steroidal saponin biosynthesis pathway."Phytochemistry. 2018 Dec;156:116 13. [IF=4.044] Feng Liu et al."Comparative analysis of proteomic and metabolomic profiles of different species of Paris."J Proteomics. 2019 May;200:11 14. [IF=5.645] Bo Li et al."Organ-specific transcriptome sequencing and mining of genes involved in polyphyllin biosynthesis in Paris polyphylla."Ind Crop Prod. 2020 Nov;156:112775 15. [IF=4.242] Shun Zhou et al."Anthelmintic efficacy of 35 herbal medicines against a monogenean parasite, Gyrodactylus kobayashii, infecting goldfish (Carassius auratus)."Aquaculture. 2020 May;521:734992 16. [IF=2.289] Zhou Shun et al."Anthelmintic efficacy of natural saponins against Gyrodactylus kobayashii in goldfish (Carassius auratus) and their 3D-QSAR analysis."Parasitol Res. 2021 Mar;120(3):1143-1150 17. [IF=4.412] Feng Su et al."Study of Chemical Compositions and Anticancer Effects of Paris polyphylla var. Chinensis Leaves."MOLECULES. 2022 Jan;27(9):2724 |
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