Propanedioic acid, sodiuM
Propanedioic acid, sodium salt
CAS: 141-95-7
Molecular Formula: C3H2Na2O4
Propanedioic acid, sodiuM - Names and Identifiers
| Name | Propanedioic acid, sodium salt |
| Synonyms | Sodium Malonate disodium propanedioate Sodium malonate dibasic Propanedioic acid, sodiuM MALONIC ACID DISODIUM SALT Malonic acid disodium salt Propanedioic acid, sodium salt Propanedioic acid, disodium salt Propanedioic acid, sodium salt Propane-1,3-dicarboxylic acid disodium propanedioic acid, monosodium salt, monohydrate Sodium malonate dibasic Malonic acid disodium salt |
| CAS | 141-95-7 |
| EINECS | 205-514-0 |
| InChI | InChI=1/C3H4O4.Na/c4-2(5)1-3(6)7;/h1H2,(H,4,5)(H,6,7);/q;+1/p-1 |
Propanedioic acid, sodiuM - Physico-chemical Properties
| Molecular Formula | C3H2Na2O4 |
| Molar Mass | 148.03 |
| Density | 2.08 g/cm3 |
| Water Solubility | Soluble in water (148 g/L at 20°C). |
| Solubility | H2O: 1M at20°C, clear, colorless |
| Appearance | Powder |
| Color | White to Almost white |
| BRN | 3917013 |
| PH | pH (50g/l, 25℃) : 8.0～10.0 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Physical and Chemical Properties | White crystals. Soluble in water, insoluble in alcohol, ether and benzene. |
Propanedioic acid, sodiuM - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| RTECS | OO1750000 |
| TSCA | Yes |
Propanedioic acid, sodiuM - Nature
Open Data Verified Data
White Crystal, soluble in water, insoluble in alcohol, ether and benzene.
Last Update：2024-01-02 23:10:35
Propanedioic acid, sodiuM - Preparation Method
Open Data Verified Data
- obtained by neutralization of malonic acid with sodium hydroxide solution.
- chloroacetic acid reacts with sodium cyanide to produce cyanoacetic acid. Then obtained by the action of liquid alkali.
Last Update：2022-01-01 10:32:34
Propanedioic acid, sodiuM - Use
Open Data Verified Data
It is used as the raw material of synergism sulfonation and barbiturate in medicine, and can also be used as the raw material of perfume and dye.
Last Update：2022-01-01 10:32:34
Propanedioic acid, sodiuM - Safety
Open Data Verified Data
This product has low toxicity. Rats were intraperitoneally injected with LD50 llo0 mg/kg, and rabbits were subcutaneously injected with the lowest lethal dose of 15 84mg/kg.
The use of plastic bags, plus woven bags. According to the general provisions of the storage and transportation of chemicals.
Last Update：2022-01-01 10:32:35
Propanedioic acid, sodiuM - Reference Information
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| uses | raw materials for the pharmaceutical industry medicines, dyes and fragrances. Dibutyl malonate is obtained by esterification of sodium malonate with butanol, and is used for production of sulfanilamide -6-methoxypyrimidine; Diethyl malonate is obtained by esterification with ethanol, and is used for production of the hypnotic barbiturate; And is also used for production of synergism-enhancing sulfonamide. for organic synthesis |
| production method | can be obtained by neutralization of malonic acid with sodium hydroxide solution. Industrial production will often chloroacetic acid and sodium cyanide reaction, generation of cyanoacetic acid, and then by the role of liquid alkali to sodium malonate. The chloroacetic acid was dissolved in water, neutralized to pH 7.0 with saturated sodium carbonate solution below 15 ℃, then sodium cyanide solution was added at 45 ℃, reacted at 105-110 ℃ for 30min, and 45-55% sodium hydroxide was added, the reaction was carried out at 100-105 ° C. For 1.5h, and the solution was concentrated and dried to obtain sodium malonate. |
Last Update：2024-04-10 22:29:15
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Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
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Product Name: Propanedioic acid, sodium salt Request for quotationCAS: 141-95-7
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
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