Pyridin-2-sulfonyl chloride
Pyridine-2-sulfonyl chloride
CAS: 66715-65-9
Molecular Formula: C5H4ClNO2S
Pyridin-2-sulfonyl chloride - Names and Identifiers
| Name | Pyridine-2-sulfonyl chloride |
| Synonyms | PYRIDINE-2-SULFONYL Vonoprazan Impurity 38 2-Pyridylsulfonyl chloride 2-Pyridinesulfonyl chloride Pyridin-2-sulfonyl chloride 2-Pyridinylsulfonyl chloride PYRIDINE-2-SULFONYL CHLORIDE Pyridine-2-sulfonyl chloride Pyridine-2-sulphonyl chloride |
| CAS | 66715-65-9 |
| InChI | InChI=1/C5H4ClNO2S/c6-10(8,9)5-3-1-2-4-7-5/h1-4H |
Pyridin-2-sulfonyl chloride - Physico-chemical Properties
| Molecular Formula | C5H4ClNO2S |
| Molar Mass | 177.61 |
| Density | 1.488 |
| Boling Point | 284℃ |
| Flash Point | 126℃ |
| Vapor Presure | 0.005mmHg at 25°C |
| pKa | -5.12±0.19(Predicted) |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.553 |
Pyridin-2-sulfonyl chloride - Introduction
Pyridine-2-sulfonyl chloride is an organic chemical with the formula C5H4ClNO2S. It is a white crystalline solid, soluble in organic solvents such as chloroform and dimethylformamide.
Pyridine-2-sulfonyl chloride are commonly used in sulfonylation reactions in organic synthesis. It can be reacted with an amino compound or an alcohol to give the corresponding sulfonyl chloride compound, or with a nucleophile to give the corresponding sulfonyl amide. It is widely used in the fields of drug synthesis, dye synthesis and pesticide synthesis.
Pyridine-2-sulfonyl chloride can be prepared by reacting pyridine with thionyl chloride. First, pyridine and thionyl chloride are heated to a reaction temperature under anhydrous conditions, followed by purification and crystallization as required, to finally obtain a Pyridine-2-sulfonyl chloride.
Pay attention to the safety information of Pyridine-2-sulfonyl chloride when using them. It is an irritating and corrosive substance, avoid contact with skin and eyes. Attention should be paid to good ventilation during operation and appropriate personal protective equipment should be used.
Pyridine-2-sulfonyl chloride are commonly used in sulfonylation reactions in organic synthesis. It can be reacted with an amino compound or an alcohol to give the corresponding sulfonyl chloride compound, or with a nucleophile to give the corresponding sulfonyl amide. It is widely used in the fields of drug synthesis, dye synthesis and pesticide synthesis.
Pyridine-2-sulfonyl chloride can be prepared by reacting pyridine with thionyl chloride. First, pyridine and thionyl chloride are heated to a reaction temperature under anhydrous conditions, followed by purification and crystallization as required, to finally obtain a Pyridine-2-sulfonyl chloride.
Pay attention to the safety information of Pyridine-2-sulfonyl chloride when using them. It is an irritating and corrosive substance, avoid contact with skin and eyes. Attention should be paid to good ventilation during operation and appropriate personal protective equipment should be used.
Last Update：2024-04-09 21:01:54
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CAS: 66715-65-9
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