Pyridine, 2,5-diiodo-
2,5-Diiodopyridine
CAS: 116195-81-4
Molecular Formula: C5H3I2N
Pyridine, 2,5-diiodo- - Names and Identifiers
| Name | 2,5-Diiodopyridine |
| Synonyms | 2,5-Diiodopyridine 2,5-DIIODOPYRIDINE Pyridine, 2,5-diiodo- |
| CAS | 116195-81-4 |
| EINECS | 627-154-7 |
| InChI | InChI=1/C5H3I2N/c6-4-1-2-5(7)8-3-4/h1-3H |
Pyridine, 2,5-diiodo- - Physico-chemical Properties
| Molecular Formula | C5H3I2N |
| Molar Mass | 330.89 |
| Density | 2.609±0.06 g/cm3(Predicted) |
| Melting Point | 152-155 °C (lit.) |
| Boling Point | 306.1±22.0 °C(Predicted) |
| Flash Point | 138.9°C |
| Water Solubility | Insoluble in water. |
| Vapor Presure | 0.00143mmHg at 25°C |
| BRN | 109261 |
| pKa | -0.18±0.10(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| Sensitive | Light Sensitive |
| Refractive Index | 1.721 |
| MDL | MFCD00234028 |
Pyridine, 2,5-diiodo- - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes R42/43 - May cause sensitization by inhalation and skin contact. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| WGK Germany | 3 |
Pyridine, 2,5-diiodo- - Introduction
2,5-Diiodopyridine is an organic compound with the chemical formula C5H2I2N. It is a yellow crystal, insoluble in water, but soluble in organic solvents such as alcohols and ethers.
2,5-Diiodopyridine is widely used as a raw material compound in organic synthesis. It can be used to synthesize drugs, pesticides, dyes and chemical reagents. It has good electrophilicity and can participate in electrophilic substitution reactions and dipole ring closure reactions.
A common method for preparing 2,5-diiodopyridine is to react 1-bromo-2, 5-diiodobenzene and pyridine under alkaline conditions, and replace the bromine atom with iodine atom through an electrophilic substitution reaction.
2,5-diiodopyridine should pay attention to safety matters during use. It is irritating to the skin and eyes, so protective gloves and glasses should be worn during operation. At the same time, its inhalation and intake should be avoided, and the operating area should be kept well ventilated. In case of accidental contact or accidental ingestion, please seek medical attention immediately.
2,5-Diiodopyridine is widely used as a raw material compound in organic synthesis. It can be used to synthesize drugs, pesticides, dyes and chemical reagents. It has good electrophilicity and can participate in electrophilic substitution reactions and dipole ring closure reactions.
A common method for preparing 2,5-diiodopyridine is to react 1-bromo-2, 5-diiodobenzene and pyridine under alkaline conditions, and replace the bromine atom with iodine atom through an electrophilic substitution reaction.
2,5-diiodopyridine should pay attention to safety matters during use. It is irritating to the skin and eyes, so protective gloves and glasses should be worn during operation. At the same time, its inhalation and intake should be avoided, and the operating area should be kept well ventilated. In case of accidental contact or accidental ingestion, please seek medical attention immediately.
Last Update：2024-04-09 21:11:58
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