Pyridine, 4-bromo-2-(trifluoromethyl)-

Pyridine, 4-bromo-2-(trifluoromethyl)- - Names and Identifiers

Name	4-bromo-2-(trifluoromethyl)pyridine
Synonyms	EOS-61272 4-Bromo-2-(trifL 4-Bromo-2-(trifluoromethyl) 4-Bromo-2-trifluoromethylpyridine 4-BROMO-2-TRIFLUOROMETHYLPYRIDINE 2-(Trifluoromethyl)-4-bromopyridine 4-bromo-2-(trifluoromethyl)pyridine pyridine, 4-bromo-2-(trifluoromethyl)- Pyridine, 4-bromo-2-(trifluoromethyl)- 4-Bromo-alpha,alpha,alpha-trifluoro-2-picoline
CAS	887583-90-6
InChI	InChI=1/C6H3BrF3N/c7-4-1-2-11-5(3-4)6(8,9)10/h1-3H

Pyridine, 4-bromo-2-(trifluoromethyl)- - Physico-chemical Properties

Molecular Formula	C6H3BrF3N
Molar Mass	225.99
Density	1.707±0.06 g/cm3(Predicted)
Boling Point	167.4±35.0 °C(Predicted)
Flash Point	55.042°C
Vapor Presure	2.248mmHg at 25°C
pKa	-1.23±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.471

Pyridine, 4-bromo-2-(trifluoromethyl)- - Introduction

4-bromo-2-(trifluoromethyl)pyridine is an organic compound with the chemical formula C6H3BrF3N. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Colorless or light yellow crystal powder
-melting point: 46-50 ℃
-Boiling point: 164-166 ℃
-Density: 1.87g/cm³
-Solubility: Soluble in common organic solvents

Use:
- 4-bromo-2-(trifluoromethyl)pyridine is an important organic synthesis intermediate for the synthesis of other compounds, such as pharmaceutically active molecules, pesticides and insecticides.
-It can also be used as a catalyst, pigment and luminescent material research field.

Preparation Method:
- 4-bromo-2-(trifluoromethyl)pyridine can be synthesized by a variety of methods, among which commonly used methods include fluorination reaction and bromination reaction.
-Fluorination reaction: 4-bromopyridine can be reacted with a trifluoromethyl compound to obtain 4-bromo-2-(trifluoromethyl)pyridine.
-Bromination reaction: The target compound can be obtained by reacting 2-trifluoromethyl-4-chloropyridine with bromine.

Safety Information:
- 4-bromo-2-(trifluoromethyl)pyridine are generally considered to be relatively safe under routine use. However, due to its chemical activity, it is still necessary to follow appropriate safety procedures.
-Personal protective equipment such as goggles, chemical protective clothing and gloves should be worn during operation.
-Avoid inhalation, contact with skin and eyes. If exposed, rinse immediately with plenty of water and seek medical assistance.
-The substance should be stored in a cool, dry and well-ventilated place, away from fire and oxidizing agents.

Last Update：2024-04-09 21:04:16