Pyridine, 5-chloro-2-nitro-
2-Nitro-5-chloropyridine
CAS: 52092-47-4
Molecular Formula: C5H3ClN2O2
Pyridine, 5-chloro-2-nitro- - Names and Identifiers
| Name | 2-Nitro-5-chloropyridine |
| Synonyms | oro-2-nitropyridine 5-Chloro-2-nitropyridine 5-CHLORO-2-NITROPYRIDINE 3-Chloro-6-nitropyridine 2-Nitro-5-chloropyridine 6-nitro-3-chloropyridine Pyridine, 5-chloro-2-nitro- |
| CAS | 52092-47-4 |
| EINECS | 639-354-1 |
| InChI | InChI=1/C5H3ClN2O2/c6-4-1-2-5(7-3-4)8(9)10/h1-3H |
Pyridine, 5-chloro-2-nitro- - Physico-chemical Properties
| Molecular Formula | C5H3ClN2O2 |
| Molar Mass | 158.54 |
| Density | 1.489±0.06 g/cm3(Predicted) |
| Melting Point | 119-123℃ |
| Boling Point | 275.3±20.0 °C(Predicted) |
| Flash Point | 120.3°C |
| Vapor Presure | 0.00865mmHg at 25°C |
| Appearance | Crystalline powder |
| pKa | -4.87±0.22(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.587 |
| MDL | MFCD03092916 |
Pyridine, 5-chloro-2-nitro- - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R50 - Very Toxic to aquatic organisms R41 - Risk of serious damage to eyes R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S37/39 - Wear suitable gloves and eye/face protection |
| UN IDs | UN 2811 6.1/PG 3 |
| WGK Germany | 2 |
| Hazard Note | Irritant |
Pyridine, 5-chloro-2-nitro- - Reference Information
| Introduction | The melting point of 2-nitro-5-chloropyridine is 119-123 ℃, the boiling point is 275.3±20.0 °C(Predicted) and the density is 1.489±0.06 g/cm3(Predicted). As a pyridine derivative, it plays an important role as an intermediate in the chemical industry and medical pesticides. |
| application | 2-nitro-5-chloropyridine can also be used as a modifier, dye aid, and synthesis of a series of products (including drugs, Disinfectants, dyes, food seasonings, adhesives, explosives, etc.). It can also be used as a catalyst, but the amount should not be too much, otherwise the product quality will be affected. |
| synthesis method | add 30% H2O2(25 mL) to concentrated H2SO4(50 mL) at 0 ℃. The solution of 5-chloropyridine-2-amine (5.0g, 39 mmol) in concentrated H2SO4(20 ml) was added at 0 ℃. Stir the mixture at room temperature for 20 hours. Pour the mixture into ice water under vigorous stirring and filter the resulting solids. The solid is recrystallized from ethanol. The final product 5-chloro-2-nitropyridine is obtained. 1H-NMR(400MHz,CDCl3)δ8.58(d,J = 2.8Hz,1H),8.23(d,J = 8.8Hz). LC/MS m/z 159(m +1)+. |
| health hazards | 2-nitro-5-chloropyridine has a stimulating effect on the eyes and upper respiratory tract. After high concentration inhalation, the light has a sense of euphoria or suffocation, followed by depression, muscle weakness, vomiting; severe loss of consciousness, incontinence, tonic spasm, blood pressure drop. Mistakes can kill you. Long-term inhalation of 2-nitro-5-chloropyridine will cause dizziness, headache, insomnia, gait instability and digestive tract dysfunction. Liver and kidney damage can occur. In addition, direct contact with 2-nitro-5-chloropyridine can cause dermatitis. |
Last Update：2024-04-09 02:00:09
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Product Name: 5-Chloro-2-Nitropyridine Visit Supplier Webpage Request for quotationCAS: 52092-47-4
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Mobile: 18021002903
QQ: 3008007409
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