Pyrimidine, 4-chloro-6-methyl- - Names and Identifiers
Pyrimidine, 4-chloro-6-methyl- - Physico-chemical Properties
Molecular Formula | C5H5ClN2
|
Molar Mass | 128.56 |
Density | 1.234 |
Melting Point | 151-152℃ |
Boling Point | 195℃ |
Flash Point | 90℃ |
Water Solubility | Slightly soluble in water. |
Vapor Presure | 0.479mmHg at 25°C |
Appearance | Solid |
Color | Pale yellow |
pKa | 0.83±0.17(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.529 |
Pyrimidine, 4-chloro-6-methyl- - Introduction
It is an organic compound with a chemical formula of C5H5ClN2 and a relative molecular mass of 130.56. The following is a description of its nature, use, preparation and safety information:
Nature:
is a colorless crystalline solid with a distinctive odor. It is stable at room temperature, but can burn. This compound is soluble in most organic solvents and has a relatively low solubility in water.
Use:
is an important organic synthesis intermediates. It is used to synthesize compounds such as pharmaceuticals, pesticides, pigments and dyes. In addition, it is widely used in chemical research and laboratories.
Preparation Method:
The preparation of the
is usually achieved by methylation and chlorination reactions. First, a pyrimidine is reacted with a methylating agent such as methyl iodide to give 4-methylpyrimidine. Then, a 4-methylchlorinating agent (e. g., chlorine) is reacted with pyrimidine to replace the hydrogen atom at the methyl position with a chlorine atom, thereby obtaining pyridine.
Safety Information:
is a harmful chemical. It has the effect of irritating the skin, eyes and respiratory tract. Appropriate protective measures must be taken during use or contact, such as wearing chemical protective glasses, gloves and respiratory protective equipment. At the same time, store it in a sealed container, away from fire and oxidizing agents to avoid fire or explosion. Be careful when handling this compound to avoid ingestion, inhalation, or contact with the skin. During use, attention should be paid to reasonable ventilation conditions and relevant safety operation procedures should be observed. If exposed or inhaled, seek medical attention immediately.
Last Update:2024-04-09 21:11:58