R-3-3'-Bis(3,5-bis(methyl)phenyl)-1,1'-bi-2-naphthol

R-3-3'-Bis(3,5-bis(methyl)phenyl)-1,1'-bi-2-naphthol - Names and Identifiers

Name	R-3-3'-Bis(3,5-bis(methyl)phenyl)-1,1'-bi-2-naphthol
Synonyms	(R)-3-3'-Bis(3,5-dimethylphenyl)-1,1'-bi-2-naphthol R-3-3'-Bis(3,5-bis(methyl)phenyl)-1,1'-bi-2-naphthol (S)-3,3'-Bis(3,5-dimethylphenyl)-[1,1'-binaphthalene]-2,2'-diol (R)-3,3'-Bis(3,5-dimethylphenyl)-1,1'-bi-2-napthalene]-2,2'-diol (R)-3,3'-Bis(3,5-dimethylphenyl)-1,1'-bi-2-naphthalene]-2,2'-diol [1,1'-Binaphthalene]-2,2'-diol, 3,3'-bis(3,5-dimethylphenyl)-, (1R)-
CAS	215433-51-5

R-3-3'-Bis(3,5-bis(methyl)phenyl)-1,1'-bi-2-naphthol - Physico-chemical Properties

Molecular Formula	C36H30O2
Molar Mass	494.62
Density	1.190±0.06 g/cm3(Predicted)
Melting Point	124-125 °C
Boling Point	597.0±45.0 °C(Predicted)
pKa	8.07±0.50(Predicted)
Storage Condition	2-8℃

R-3-3'-Bis(3,5-bis(methyl)phenyl)-1,1'-bi-2-naphthol - Introduction

(R)-3,3 '-Bis (3,5-bismethylphenyl)-1,1'-binaphthol is an organic compound with the chemical formula C44H38O2, it is a solid substance insoluble in water. This compound is often abbreviated as R-BINOL.

R-BINOL is a chiral compound with two chiral centers, so there are four stereoisomers. Here,(R)-BINOL refers to an isomer with right-handed rotation at both chiral centers.

R-BINOL has important applications in asymmetric synthesis and catalytic reactions. Due to its chiral properties, it is often used as a chiral recognition reagent, a catalyst for Chiral separation, and a precursor for the preparation of chiral drugs and chiral small molecules.

The preparation R-BINOL can be obtained by The iodination reaction of binaphthol and the condensation reaction of benzyl alcohol. The specific preparation method is complicated and needs to be operated under specific temperature and conditions.

Based on the available information, R-BINOL is not currently identified as a toxic substance. However, when using this compound, it is recommended to follow general laboratory safety regulations and operating procedures, avoid direct contact with the skin and inhalation of its dust.

Last Update：2024-04-09 20:49:11