RMI 10874 - Names and Identifiers
RMI 10874 - Physico-chemical Properties
Molecular Formula | C21H26N2O4
|
Molar Mass | 370.44 |
In vivo study | The effect of RMI 10874 (RMI 10,874DA) in the abrogation of the metastatic spread of tumor cells is studied. Pre-treatment of BALB/c mice with the RMI 10,874DA completely eliminates lung colonization of an H-2-negative (GR9.B9) MCA-induced fibrosarcoma clone in an experimental metastasis assay. The effect of a tilorone analogue (RMI 10,874DA) and anti-asialo GM 1 serum is studied on the survival of BALB/c and C57B1/6 mice after i.v. injections of different syngeneic murine tumor cells. Natural killer (NK) cell activation in vivo by RMI 10874 prolongs survival and inhibits metastasis formation in mice, even when pretreatment consists of a single dose of the analogue. Tilorone is a small-molecule, orally bioavailable drug that is used clinically as an antiviral. |
RMI 10874 - Introduction
RMI 10874 is an organic compound that is a colorless liquid in nature. It is an aromatic amine compound, soluble in organic solvents such as ethers and ketones, and insoluble in water.
The main use of RMI 10874 is as a catalyst precursor, especially in organic synthesis. It can be used in the synthesis of polymer materials, pharmaceuticals and pesticides and other compounds.
The preparation method of RMI 10874 can be achieved by the reaction of diarylamine and fluorine-containing aryl acid. In General, reacting a diarylamine with a fluorine-containing aryl acid under appropriate reaction conditions can give a RMI 10874.
Regarding the safety information of RMI 10874, you need to pay attention to the following points:
1. RMI 10874 are potentially irritating and toxic, and care should be taken to avoid skin contact and inhalation.
2. When using and handling RMI 10874, it is recommended to wear appropriate protective equipment, such as gloves and goggles.
3. It should be operated in a well-ventilated place and kept away from fire and high temperature environment.
4. Need to properly store RMI 10874, away from moisture and direct sunlight.
In general, you need to use caution when using RMI 10874 and follow the safety procedures of the relevant chemical laboratory.
Last Update:2024-04-09 19:05:03