Raspberry extract
Ellagic acid
CAS: 476-66-4
Molecular Formula: C14H6O8
Raspberry extract - Names and Identifiers
| Name | Ellagic acid |
| Synonyms | lagistase C.I. 75270 C.I. 55005 eleagicacid ELLAGIC ACID Ellagic acid AKOS NCG1-0028 BENZOARIC ACID Raspberry extract TIMTEC-BB SBB006501 gallogen(astringent) ellagic acid from chestnut bark 2,3,7,8-tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione 2,3,7,8-tetrahydroxy(1)benzopyrano(5,4,3-cde)(1)benzopyran-5,10-dione |
| CAS | 476-66-4 |
| EINECS | 207-508-3 |
| InChI | InChI=1/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H |
| InChIKey | AFSDNFLWKVMVRB-UHFFFAOYSA-N |
Raspberry extract - Physico-chemical Properties
| Molecular Formula | C14H6O8 |
| Molar Mass | 302.19 |
| Density | 1.667 |
| Melting Point | ≥350°C |
| Boling Point | 363.24°C (rough estimate) |
| Flash Point | 310.1°C |
| Water Solubility | <0.1 g/100 mL at 21 ºC |
| Solubility | Slightly soluble in water and alcohol, soluble in alkali and pyridine, insoluble in ether. |
| Vapor Presure | 2.32E-26mmHg at 25°C |
| Appearance | Yellow needle crystal |
| Color | tan to gray |
| Merck | 14,3547 |
| BRN | 47549 |
| Storage Condition | 2-8°C |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| Sensitive | Air & Light Sensitive |
| Refractive Index | 1.5800 (estimate) |
| MDL | MFCD00006914 |
| Physical and Chemical Properties | Density 1.667 melting point> 360°C water-soluble <0.1g/100 mL at 21°C |
| Use | Used in medicine and cosmetics, as an antioxidant, with anti-cancer and Virus inhibition |
Raspberry extract - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37 - Wear suitable protective clothing and gloves. |
| WGK Germany | 3 |
| RTECS | DJ2620000 |
| FLUKA BRAND F CODES | 8-10-23 |
| HS Code | 29322090 |
| Toxicity | LD50 oral in rat: > 20gm/kg |
Raspberry extract - Nature
Open Data Verified Data
pure ellagic acid is milky white crystal, melting point at 360 deg C (decomposition). The impure extract is a white or pale yellow powder crystal or liquid, slightly soluble in water and ethanol. Ellagic acid contains four phenolic hydroxyl groups, with weak acidity, soluble in alkaline aqueous solution and benzene, ethyl acetate and other organic solvents. Ellagic acid has good heat resistance, and still does not decompose when heated above 150 ℃ for 6h, and has good oxidation resistance.
Last Update：2024-01-02 23:10:35
Raspberry extract - Preparation Method
Open Data Verified Data
It is mainly extracted from plants, and there are more abundant in the leaves of gallnut, fruit of water chestnut, fruit of landrace tree and Eucalyptus globulus, usually, the raw material is degreased and then extracted with an alkaline aqueous solution or ethanol, and then the water soluble protein and the alcohol soluble protein are removed, and then the pure ellagic acid can be prepared by enzymatic decomposition and removing the sugar ligand.
Last Update：2022-01-01 11:13:13
Raspberry extract - Use
Open Data Verified Data
can be used as a food antioxidant. Generally used after mixing with VE, Vc or gallic acid. In addition, ellagic acid has anti-cancer/anti-mutation properties, Virus inhibition of human immunodeficiency, inhibition of a variety of bacteria, Virus have a role in lowering blood pressure, sedation.
Last Update：2022-01-01 11:13:13
Raspberry extract - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| introduction | ellagic acid is a natural organic substance, which mostly exists in some fruits and nuts. it is a natural polyphenol substance. this substance will turn blue when encountering ferric chloride and yellow when encountering sulfuric acid. after being absorbed by human body, this substance can improve human body's anti-cancer ability and nourish skin. |
| effect | ellagic acid can remove melanin in the body after being absorbed by the human body, can accelerate the decomposition of melanin, and can prevent melanin from accumulating on the skin surface. it can also prevent melanin from forming from the root, prevent stains on the surface of human skin, and can also play a certain whitening effect, therefore, this substance is widely used in the production of cosmetics and medicines. |
| biological activity | Ellagic acid (Elagostasine, Gallogen) has anti-proliferation and anti-oxidation properties. |
| Target | Value |
| Uses | A common plant polyphenol, an inhibitor of glutathione S-transferase. It can be used for the determination of factor XIIa in plasma. Contact activation can occur during blood coagulation. Used in medicine and cosmetics, as an antioxidant, with anti-cancer and virus inhibition effects Commonly found in polyphenol plants. An inhibitor of glutathione S-transferase, often used to detect factor XIIa in plasma; antioxidants; protective agents of DNA double strands. |
| production method | is mainly extracted from plants. it is abundant in the leaves of galla, water chestnut fruit, olive fruit and eucalyptus. usually, the raw materials are degreased and extracted with alkaline aqueous solution or ethanol, and then water-soluble protein and gliadin are removed, the purified ellagic acid can be prepared by decomposing the sugar ligand with enzyme. |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 20:48:19
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