Name | (+)-Polyneuridine |
Synonyms | Rhazin Rhazine Akuammidine (+)-Polyneuridine 17-Hydroxysarpagane-16-carboxylic acid methyl ester SARPAGAN-16-CARBOXYLIC ACID17-HYDROXY-,METHYL ESTER |
CAS | 639-36-1 |
Molecular Formula | C21H24N2O3 |
Molar Mass | 352.43 |
Density | 1.34±0.1 g/cm3(Predicted) |
Melting Point | 243-246℃ |
Boling Point | 513.0±50.0 °C(Predicted) |
pKa | 14.79±0.10(Predicted) |
Storage Condition | 2-8℃ |
In vitro study | Akuammidine treatment decreases the expression of IL-6 in cells. |
biological activity | Akuammidine can be extracted from the seeds of Picralima nitida-, ki values for the Sigma-and kappa-opioid receptors were 0.6 μm, 2.4 μm and 8.6 μm, respectively. Akuammidine has anti-inflammatory and antiasthmatic effects. |