Name | sym-Dimethylethylenediamine |
Synonyms | DMEN DMEDA ethylhydrazine 1,2-Bis(methylamino)ethane sym-Dimethylethylenediamine N,N'-Dimethylethylenediamine N,N'-DimethylethyleneDiamines N,N'-Dimethyl-1,2-ethanediamine N,N'-dimethylethane-1,2-diamine N,N'-dimethylethane-1,2-diaminium Symmetrical dimethylethylenediamine N,N'-Dimethylethylenediamine, Technical Grade |
CAS | 110-70-3 |
EINECS | 203-793-3 |
InChI | InChI=1/C4H12N2/c1-5-3-4-6-2/h5-6H,3-4H2,1-2H3/p+2 |
InChIKey | KVKFRMCSXWQSNT-UHFFFAOYSA-N |
Molecular Formula | C4H12N2 |
Molar Mass | 88.15 |
Density | 0.819g/mLat 20°C(lit.) |
Melting Point | 1.63°C (estimate) |
Boling Point | 119°C(lit.) |
Flash Point | 83°F |
Solubility | Miscible with chloroform and dichloromethane. |
Vapor Presure | 15.5mmHg at 25°C |
Appearance | Colorless liquid |
Specific Gravity | 0.828 |
Color | Clear colorless to slightly yellow |
BRN | 878142 |
pKa | 10.54±0.10(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
Sensitive | Air Sensitive |
Refractive Index | n20/D 1.431(lit.) |
MDL | MFCD00008290 |
Use | For use in organic synthesis or as a pharmaceutical Intermediate |
Hazard Symbols | C - Corrosive |
Risk Codes | R10 - Flammable R34 - Causes burns R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S16 - Keep away from sources of ignition. |
UN IDs | UN 2734 8/PG 2 |
WGK Germany | 3 |
RTECS | KV4250000 |
TSCA | Yes |
HS Code | 29212900 |
Hazard Class | 3 |
Packing Group | III |
NIST chemical information | Information provided by: webbook.nist.gov (external link) |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
Application | N,N'-dimethylethylenediamine is an amine compound and can be used as a pharmaceutical intermediate. N,N-dimethyl ethylenediamine is an important fine chemical product. As an important pharmaceutical intermediate, it can be used to synthesize anti-tumor drugs thioxanthone (thioxanthenone), carbamoyl fish vine, anti-arrhythmic drug procainamide (procainemide), local anesthetic dibukaine (dibucain), antihistamine Hytramine (neo- hetranine), anticholinesterphthalein drug Ambeguanide (I. e. enzyme-yining), cefazolin sodium (Pioneer No. 5), etc. It is used in agriculture to synthesize flower inducers. It is also used as a series of additives (such as fixing agent, wetting agent, fiber softener and antistatic agent, BCH), reactive cationic dye intermediates, ion exchange resins and epoxy resin curing agents. |
prepare | ethanolamine as the starting material, and react with human hydrogen chloride gas in ethanol medium to obtain ethanolamine chloride with a yield of 52%; The obtained product reacts with thionyl chloride to obtain chloroethylamine chloride with a yield of 71 .4%; The obtained product is then reacted with dimethylamine to obtain a 75%-purpose product after treatment. If ethanolamine is used, the total yield is 27.8%. |
Use | Used in organic synthesis or as a pharmaceutical intermediate |