TASOSARTAN

Name	Tasosartan
Synonyms	ANA-756 DB01349 AC1L1U5X AC1Q6LAA TASOSARTAN Tasosartan S1539_Selleck 2,4-Dimethyl-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-5,6-dihydropyrido[6,5-d]pyrimidin-7-one 5,8-Dihydro-2,4-dimethyl-8-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]pyrido[2,3-d]pyrimidin-7(6H)-one
CAS	145733-36-4

Molecular Formula	C23H21N7O
Molar Mass	411.46
Density	1.328±0.06 g/cm3(Predicted)
Melting Point	197-199°
Boling Point	759.4±70.0 °C(Predicted)
Solubility	DMSO (Slightly), Methanol (Slightly, Sonicated)
Appearance	Solid
Color	White to Off-White
pKa	4.16±0.10(Predicted)
Storage Condition	2-8°C
In vitro study	Tasosartan is an orally active nonpeptide AngII antagonist that has demonstrates specific and selective AT1 receptor antagonistic activity in vitro. IC 50 for inhibition of specific binding of 125 I-AngII to rat adrenal membrane in the absence of proteins in binding buffer is 1.2±0.6 nM.
In vivo study	Administration of Tasosartan at doses of 1.0 and 3.0 mg/kg (iv) significantly (p<0.05) attenuates the pressor response to angiotensin-II in rats.

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Product Name: Tasosartan Visit Supplier Webpage Request for quotation
CAS: 145733-36-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

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TASOSARTAN

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