TIMTEC-BB SBB000766
6-hydroxy-2-phenyl-4-benzopyrone
CAS: 6665-83-4
Molecular Formula: C15H10O3
TIMTEC-BB SBB000766 - Names and Identifiers
| Name | 6-hydroxy-2-phenyl-4-benzopyrone |
| Synonyms | NSC 26744 6-HYDROXYFLAVONE 6-Hydroxyflavone HYDROXYFLAVONE, 6- TIMTEC-BB SBB000766 HYDROXYFLAVONE, 6-(RG) 6-Hydroxy-2-phenyl-4-benzopyrone 6-hydroxy-2-phenyl-4-benzopyrone 6-hydroxy-2-phenyl-4H-chroMen-4-one 6-hydroxy-2-phenyl-4H-chromen-4-one |
| CAS | 6665-83-4 |
| EINECS | 229-704-8 |
| InChI | InChI=1/C15H10O3/c16-11-6-7-14-12(8-11)13(17)9-15(18-14)10-4-2-1-3-5-10/h1-9,16H |
TIMTEC-BB SBB000766 - Physico-chemical Properties
| Molecular Formula | C15H10O3 |
| Molar Mass | 238.24 |
| Density | 1.2653 (rough estimate) |
| Melting Point | 234-236 °C (lit.) |
| Boling Point | 320.83°C (rough estimate) |
| Flash Point | 176.3°C |
| Vapor Presure | 1.02E-08mmHg at 25°C |
| Appearance | Pale yellow crystal |
| Color | Light yellow to Yellow to Green |
| BRN | 15827 |
| pKa | 8.98±0.40(Predicted) |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.5740 (estimate) |
| MDL | MFCD00017329 |
TIMTEC-BB SBB000766 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| Hazard Note | Irritant |
TIMTEC-BB SBB000766 - Reference
| Reference Show more | 1. Luo, Y, Wu, C, Liu, L, et al. 3-Hydroxyflavone enhances the toxicity of ZnO nanoparticles in vitro. J Appl Toxicol. 2018; 38: 1206– 1214. https://doi.org/10.1002/jat.3633 2. Zhang, Cao, et al. "Chemical structures of polyphenols that critically influence the toxicity of ZnO nanoparticles." Journal of agricultural and food chemistry 66.7 (2018): 1714-1722.https://doi.org/10.1021/acs.jafc.8b00368 3. [IF=5.279] Cao Zhang et al."Chemical Structures of Polyphenols That Critically Influence the Toxicity of ZnO Nanoparticles."J Agr Food Chem. 2018;66(7):1714–1722 4. [IF=3.446] Yunfeng Luo et al."3-Hydroxyflavone enhances the toxicity of ZnO nanoparticles in vitro."J Appl Toxicol. 2018 Sep;38(9):1206-1214 |
TIMTEC-BB SBB000766 - Reference Information
| Introduction | 6-hydroxyflavone is a flavonoid that is a non-competitive inhibitor of the cytochrome P450 enzyme CYP2C9. 6-hydroxyflavone can be found in the leaves of Rhododendron Aurea (scientific name: Barleria prionitis) and may be a potential drug for the treatment of Anxiety-like disorders. |
| biological activity | 6-Hydroxyflavone is a naturally occurring flavonoid compound with anti-inflammatory properties. 6-Hydroxyflavone has an inhibitory effect on the glycosylation of bovine hemoglobin (BHb). 6-Hydroxyflavone can activate AKT, ERK 1/2, JNK signaling pathway, and effectively promote osteoblast differentiation. 6-Hydroxyflavone inhibits LPS-induced NO production. |
Last Update：2024-04-09 21:32:07
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Spot supply
Product Name: 6-Hydroxyflavone Visit Supplier Webpage Request for quotationCAS: 6665-83-4
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Multiple SpecificationsSpot supply
Product Name: 6-Hydroxyflavone Visit Supplier Webpage Request for quotationCAS: 6665-83-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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