TIMTEC-BB SBB011045
1-Allyl-6-fluoro-1H-indole-3-carbaldehyde
CAS: 883543-88-2
Molecular Formula: C12H10FNO
TIMTEC-BB SBB011045 - Names and Identifiers
TIMTEC-BB SBB011045 - Physico-chemical Properties
| Molecular Formula | C12H10FNO |
| Molar Mass | 203.21 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD07790765 |
TIMTEC-BB SBB011045 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
TIMTEC-BB SBB011045 - Introduction
A (1-allyl-6-fluoro-1H-indole-3-carbaldehyde) is an organic compound. Its chemical formula is C11H8FNO and has a molecular weight of 189.18g/mol. The following is a detailed description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: It is a yellow to orange crystal or powder form.
-Solubility: It is almost insoluble in water, but soluble in organic solvents such as methanol and ethanol.
-Melting point and boiling point: The melting point of the compound is 76-78°C.
-Optical properties: It has chirality and can exist in two stereoisomers.
Use:
-Chemical intermediate: It is an important organic synthesis intermediate that can be used to prepare various compounds containing indole structures.
-Drug research: It is used in the field of drug research to synthesize new drugs and drug candidates.
Preparation Method:
The preparation method can be carried out by the following steps:
1.1-propenyl -2-fluoroacetophenone reacts with indole at low temperature to generate 1-allyl -2-(indole -3-yl) ethanone.
2.1-allyl -2-(indole -3-yl) ethanone reacts with hydrogen cyanide to generate 1-allyl -2-(indole -3-yl) acetonitrile.
3.1-allyl-2-(indol-3-yl) acetonitrile was converted to 1-allyl-6-fluoro-1H-indole-3-carbaldehyde using an aldoylation reaction.
Safety Information:
-in the operation need to pay attention to prevent inhalation, contact with eyes and skin, and avoid ingestion.
-During operation, please wear suitable protective equipment, such as gloves, glasses and protective clothing.
-If contact occurs, immediately flush the affected area with plenty of water and seek medical help.
-When storing, keep the compound in a dry, cool place away from fire and oxidizing agents.
Nature:
-Appearance: It is a yellow to orange crystal or powder form.
-Solubility: It is almost insoluble in water, but soluble in organic solvents such as methanol and ethanol.
-Melting point and boiling point: The melting point of the compound is 76-78°C.
-Optical properties: It has chirality and can exist in two stereoisomers.
Use:
-Chemical intermediate: It is an important organic synthesis intermediate that can be used to prepare various compounds containing indole structures.
-Drug research: It is used in the field of drug research to synthesize new drugs and drug candidates.
Preparation Method:
The preparation method can be carried out by the following steps:
1.1-propenyl -2-fluoroacetophenone reacts with indole at low temperature to generate 1-allyl -2-(indole -3-yl) ethanone.
2.1-allyl -2-(indole -3-yl) ethanone reacts with hydrogen cyanide to generate 1-allyl -2-(indole -3-yl) acetonitrile.
3.1-allyl-2-(indol-3-yl) acetonitrile was converted to 1-allyl-6-fluoro-1H-indole-3-carbaldehyde using an aldoylation reaction.
Safety Information:
-in the operation need to pay attention to prevent inhalation, contact with eyes and skin, and avoid ingestion.
-During operation, please wear suitable protective equipment, such as gloves, glasses and protective clothing.
-If contact occurs, immediately flush the affected area with plenty of water and seek medical help.
-When storing, keep the compound in a dry, cool place away from fire and oxidizing agents.
Last Update：2024-04-09 19:06:00
