Thalidomide 5-Aminoisoindoline Impurity - Names and Identifiers
Name | 5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
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Synonyms | Pomalidomide Impurity F Pomalidomide Impurity 25 Thalidomide 5-Aminoisoindoline Impurity 5-amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione 5-amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione 5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 5-Amino-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione 1H-Isoindole-1,3(2H)-dione, 5-amino-2-(2,6-dioxo-3-piperidinyl)-
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CAS | 191732-76-0
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Thalidomide 5-Aminoisoindoline Impurity - Physico-chemical Properties
Molecular Formula | C13H11N3O4
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Molar Mass | 273.24414 |
Density | 1.570±0.06 g/cm3(Predicted) |
Melting Point | >300 °C |
Boling Point | 603.8±50.0 °C(Predicted) |
Solubility | Aqueous Base (Slightly), DMSO (Slightly, Sonicated) |
Appearance | Solid |
Color | Green to Dark Green |
pKa | 10.83±0.40(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Thalidomide 5-Aminoisoindoline Impurity - Introduction
5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione(5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione) is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione is a white crystalline or crystalline powder. It is insoluble in water at room temperature and slightly soluble in common organic solvents such as ethanol and dimethyl sulfoxide. Its chemical formula is C13H11N3O4 and its molecular weight is 281.25.
Use:
5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione is mainly used as a drug intermediate and plays an important role in the pharmaceutical industry. It can be used to synthesize a variety of drugs, such as anti-cancer drugs and anti-inflammatory drugs.
Method:
5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1, the preparation method of 3-dione can be achieved through multi-step chemical reactions. Specifically, the target product can be synthesized from a starting material having an appropriate structure through a series of reaction steps.
Safety Information:
Relatively limited information is available on the safety and toxicity of 5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione. However, when handling and using the substance, appropriate safety measures should be taken, such as wearing protective gloves and glasses, ensuring good ventilation conditions, and avoiding inhalation or skin contact. When using the substance, the relevant safety procedures and guidelines should be followed. For detailed safety information, reference should be made to the Material Safety Data Sheet (MSDS) provided by the supplier.
Last Update:2024-04-09 21:54:55