Name | toluidine blue |
Synonyms | toluidine blue Toluidine bule, BS TOLUIDINE BLUE C.I. No 52040 TOLUIDINE BLUE FOR MICROSCOPY Toluidine Blue, for microscopy (Hist., Vit.) N-(7-amino-8-methyl-3H-phenothiazin-3-ylidene)-N-methylmethanaminium chloride (7-amino-8-methylphenothiazin-3-ylidene)-dimethylazanium,dichlorozinc,dichloride Zinc chloride compd. with 3-amino-7-(dimethylamino)-2-methylphenothiazin-5-ium chloride Phenothiazin-5-ium, 3-amino-7-(dimethylamino)-2-methyl-, chloride, compd. with zinc chloride (ZnCl2) |
CAS | 6586-04-5 |
EINECS | 202-146-2 |
InChI | InChI=1/C15H15N3S.ClH/c1-9-6-13-15(8-11(9)16)19-14-7-10(18(2)3)4-5-12(14)17-13;/h4-8,16H,1-3H3;1H |
Molecular Formula | C15H16Cl3N3SZn |
Molar Mass | 442.1 |
BRN | 4068052 |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
HS Code | 32041300 |
Color index | 52040 |
Overview | Toluidine blue also known as Toluidine blue; 2,2 '-[(9, 10-dihydro-4, 8-dihydroxy-9, 10-dioxo-1, 5-anthracenediyl) diamino] bis (5-methylbenzenesulfonic acid) disodium salt; Toluidine blue/Toluidine blue; toluidine blue O. as photosensitizer gel, Toluidine Blue has the following advantages: gel preparation has a certain viscosity and adhesion, can make the drug stay in the diseased area to improve the therapeutic effect. On the other hand, Toluidine blue is a nucleic acid-prone eosinophilic dye that resides in tissues with more nuclear components. Has a good penetration depth in the tissue, can be effectively distributed in the infected target tissue, but can not penetrate the normal tissue, so as to avoid the normal tissue by photodynamic killing, therefore, Toluidine Blue has good selectivity to the lesion area and bacteria. The most important point is that the Toluidine blue photosensitizer has no obvious toxic and side effects, which reduces the harm to the human health system and is conducive to the promotion and application of photodynamic therapy. |
Use | redox indicator. Biological Stain. Histochemistry is used for the determination of deoxyribonucleic acid and ribonucleic acid. Diagnosis was diphtheria. Dyeing of wool and silk. |