Udenafil(DA 8159,Zydena)

Name	Udenafil
Synonyms	Zydena CS-1353 Udenafil Udenafil, DA 8159 Udenafil(DA 8159,Zydena) 5-[2-propyloxy-5-[2-(1-Methyl-2-pyrrolidinyl)ethylaMinosulfonyl]phenyl]-1-Methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyriMidine-7-one 5-[2-propyloxy-5-(2-(1-Methylpyrrolidin-2-yl)ethylaMinosulphonyl)phenyl]-1-Methyl-3-propyl-6,7-dihydro-1H-pyrazolo(4,3-d)pyriMidin-7-one BenzenesulfonaMide,3-(6,7-dihydro-1-Methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyriMidin-5-yl)-N-[2-(1-Methyl-2-pyrrolidinyl)ethyl]-4-propoxy-
CAS	268203-93-6

Molecular Formula	C25H36N6O4S
Molar Mass	516.66
Density	1.35
Melting Point	152-159°C
Boling Point	697.0±65.0 °C(Predicted)
Solubility	Chloroform (Slightly), Methanol (Sparingly)
Appearance	Solid
Color	White to Pale Beige
pKa	11.07±0.50(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
In vitro study	The inhibitory effect of Udenafil on PDE5 was approximately 150 times stronger than that of pde1. At therapeutic doses of Udenafil (effective doses to inhibit PDE5), the likelihood of inhibiting PDE11 is low. The IC50 values of Udenafil for PDE2, PDE3, and PDE6 were 101±15.1 nM, 52.0±3.53 nM, and 53.3±2.47 nM, respectively.

Last Update：2024-01-02 23:10:35

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Udenafil(DA 8159,Zydena)

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