Z-Thr(tBu)-OH dicyclohexylamine salt
N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt
CAS: 16966-07-7
Molecular Formula: C28H46N2O5
Z-Thr(tBu)-OH dicyclohexylamine salt - Names and Identifiers
| Name | N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt |
| Synonyms | Z-Thr(tBu)-OH·DCHA Z-Thr(Tbu)-Oh Dcha Z-Thr(tBu)-OH.DCHA Z-Thr(But)-OH*DCHA Z-THR(TBU)-OH DCHA SALT Cbz-DL-Thr(tBu)-OH DCHA Z-THREONINE(TBU)-OH DCHA Z-T-BUTYL-L-THREONINE DCHA SALT Z-Thr(tBu)-OH dicyclohexylamine salt Z-O-tert.butyl-L-threoninedicyclohexylamine salt Z-O-tert·butyl-L-threoninedicyclohexylamine salt N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt N-Benzyloxycarbonyl-O-tert-butyl-L-threonine dicyclohexylamine N-benzyloxycarbonyl-O-tert-butyl-L-threonine, compound with dicyclohexylamine |
| CAS | 16966-07-7 |
| EINECS | 241-040-0 |
| InChI | InChI=1/C16H23NO5.C12H23N/c1-11(22-16(2,3)4)13(14(18)19)17-15(20)21-10-12-8-6-5-7-9-12;1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h5-9,11,13H,10H2,1-4H3,(H,17,20)(H,18,19);11-13H,1-10H2/t11?,13-;/m0./s1 |
Z-Thr(tBu)-OH dicyclohexylamine salt - Physico-chemical Properties
| Molecular Formula | C28H46N2O5 |
| Molar Mass | 490.68 |
| Melting Point | 143-147°C |
| Boling Point | 636.3°C at 760 mmHg |
| Flash Point | 338.6°C |
| Vapor Presure | 4.58E-17mmHg at 25°C |
| Appearance | Solid |
| Storage Condition | Inert atmosphere,2-8°C |
Z-Thr(tBu)-OH dicyclohexylamine salt - Risk and Safety
| WGK Germany | 3 |
Z-Thr(tBu)-OH dicyclohexylamine salt - Introduction
N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt is an organic compound with the following properties:
1. Appearance: white or white crystal powder.
2. Solubility: soluble in organic solvents, such as methanol and ethanol, almost insoluble in water.
3. Melting point: about 160-165 ° C.
N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt is often used as a synthetic intermediate for the following purposes:
1. Impedance agent: In synthetic drugs, it is often used to prepare potential amino acid-based drugs.
2. Protecting group: it can be used to protect amino acids in organic synthesis to prevent side reactions in the reaction process.
3. Drug formulation: It can be used as a part of the drug formulation to improve its solubility and stability.
The preparation method of N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt is as follows:
1. In the presence of sulfur hexachloride, tert-butoxycarbonylchloromethyl is reacted with L-threonine to obtain N-Cbz-O-tert-butoxycarbonyl-L-threonine monohydrochloride.
2. N-Cbz-O-tert-butoxycarbonyl-L-threonine monohydrochloride is reacted with dicyclohexylamine under alkaline conditions to generate the N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt.
Regarding safety information, N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt is a compound, you need to pay attention to the following matters during operation:
1. Avoid inhalation: Wear a suitable protective mask to prevent dust, smoke or gas from entering the respiratory system.
2. Avoid contact with skin and eyes: Use protective gloves and goggles to protect the skin and eyes to reduce direct contact of the compound to the skin and eyes.
3. Pay attention to the fire Source: avoid the compound from contact with the fire source or electrostatic discharge to prevent fire and explosion.
4. Storage conditions: should be stored in a dry, cool place, away from open flames and oxidants.
It should be emphasized that the information provided above is for reference only. The specific use and operation should follow the safety operation guidelines and laboratory operation specifications of relevant chemicals.
1. Appearance: white or white crystal powder.
2. Solubility: soluble in organic solvents, such as methanol and ethanol, almost insoluble in water.
3. Melting point: about 160-165 ° C.
N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt is often used as a synthetic intermediate for the following purposes:
1. Impedance agent: In synthetic drugs, it is often used to prepare potential amino acid-based drugs.
2. Protecting group: it can be used to protect amino acids in organic synthesis to prevent side reactions in the reaction process.
3. Drug formulation: It can be used as a part of the drug formulation to improve its solubility and stability.
The preparation method of N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt is as follows:
1. In the presence of sulfur hexachloride, tert-butoxycarbonylchloromethyl is reacted with L-threonine to obtain N-Cbz-O-tert-butoxycarbonyl-L-threonine monohydrochloride.
2. N-Cbz-O-tert-butoxycarbonyl-L-threonine monohydrochloride is reacted with dicyclohexylamine under alkaline conditions to generate the N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt.
Regarding safety information, N-Z-O-tert-butyl-L-threonine dicyclo-hexylamine salt is a compound, you need to pay attention to the following matters during operation:
1. Avoid inhalation: Wear a suitable protective mask to prevent dust, smoke or gas from entering the respiratory system.
2. Avoid contact with skin and eyes: Use protective gloves and goggles to protect the skin and eyes to reduce direct contact of the compound to the skin and eyes.
3. Pay attention to the fire Source: avoid the compound from contact with the fire source or electrostatic discharge to prevent fire and explosion.
4. Storage conditions: should be stored in a dry, cool place, away from open flames and oxidants.
It should be emphasized that the information provided above is for reference only. The specific use and operation should follow the safety operation guidelines and laboratory operation specifications of relevant chemicals.
Last Update：2024-04-09 20:02:46
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