ZWISCHENFERMENT TYPE V
glucose-6-phosphate dehydrogenase
CAS: 9001-40-5
Molecular Formula:
ZWISCHENFERMENT TYPE V - Names and Identifiers
| Name | glucose-6-phosphate dehydrogenase |
| Synonyms | ZWISCHENFERMENT ZWISCHENFERMENT G6P-DH ZWISCHENFERMENT TYPE V ZWISCHENFERMENT TYPE IX ZWISCHENFERMENT TYPE XV ZWISCHENFERMENT TYPE VII glucose-6-phosphate dehydrogenase Glucose -6-phosphoric acid dehydrogenase glucose-6-phosphate dehydrogenase from baker's yeast (s. cerevisiae) |
| CAS | 9001-40-5 |
| EINECS | 232-602-6 |
ZWISCHENFERMENT TYPE V - Physico-chemical Properties
| Melting Point | ～120℃ |
| Water Solubility | Soluble in water and dilute buffer. |
| Appearance | suspension |
| Color | white |
| Storage Condition | -20°C |
| MDL | MFCD00081656 |
| Physical and Chemical Properties | It is a suspension suspended in 3.2mol · L-1 ammonium sulfate solution extracted from yeast. Ph is 6, each containing 700 units, which is equivalent to 140 units per mg. |
| Use | ) is an enzyme in red blood cell glucose metabolism. Its function is to maintain reduced glutathione and reduced coenzyme II (NADPH), maintain the reducing ability in red blood cells, and prevent hydrogen peroxide from damaging red blood cells. In addition, it can catalyze the dehydrogenation reaction of glucose -6-phosphate, and can be used for enzymatic detection of NAD (or NADP), glucose -6-phosphate, glucose-phosphate isomerase, glucose-phosphate mutase and hexokinase. It is combined with hexokinase for enzymatic detection of glucose |
ZWISCHENFERMENT TYPE V - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 3-10 |
| TSCA | Yes |
| HS Code | 35079090 |
ZWISCHENFERMENT TYPE V - Reference
| Reference Show more | 1. Wang, Xiaowan. Regulation mechanism of Escherichia coli lipopolysaccharide on synthesis of lauric acid [D]. Jiangnan University, 2020. 2. Sun, Dongxue, et al. "Coupling p-Hydroxybenzoate." Sensors and Actuators B: Chemical 327 (2021): 128859.https://doi.org/10.1016/j.snb.2020.128859 3. [IF = 1.908] Yan Liu et al. "Study on the pharmacogenetics of deoxyschizandrin and schizandrin combination with epigallocatechin gallate, a component of green tea, in rats."Xenobiotica. 2018;48(4):412-421 4. [IF=4.155] Siqi Zhang et al."Step-wise immobilization of multi-enzymes by zirconium-based coordination polymer in situ self-assembly and specific absorption."J Inorg Biochem. 2020 Jul;208:111093 |
ZWISCHENFERMENT TYPE V - Trait
White amorphous powder.
Last Update：2023-08-16 21:32:38
ZWISCHENFERMENT TYPE V - Vitality definition
one unit causes the formation of one micromole of NADH per minute at pH7.8 at 30℃
Last Update：2023-08-16 21:32:38
ZWISCHENFERMENT TYPE V - Vitality
≥150 units/mg solid
Last Update：2023-08-16 21:32:38
ZWISCHENFERMENT TYPE V - Specific vitality
≥400units/mg protein
Last Update：2023-08-16 21:32:38
ZWISCHENFERMENT TYPE V - Reference Information
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Introduction | glucose-6-phosphate dehydrogenase,EC 1.1.1.49 it is an oxidoreductase that acts on the donor CH-OH group with NAD or NADP as an acceptor. This enzyme catalyzes the following enzymatic reactions: Glucose -6-phosphate dehydrogenase is mainly involved in the pentose phosphate pathway and also acts slowly on other sugars such as β-D-glucose. This enzyme can be activated by its substrate glucose -6-phosphate, if the human expression of glucose -6-phosphate dehydrogenase gene G6PD is defective, it will lead to glucose -6-phosphate dehydrogenase deficiency, causes non-immune hemolytic anemia. |
| Use | commonly used diagnostic enzymes. Biochemical studies. The coupling reaction of glucose and creatine kinase in blood and urine was determined. used in biochemical research, is an enzyme in Erythrocyte Glucose metabolism, its role is to maintain reduced glutathione and reduced coenzyme II (NADPH), maintain the reduction ability of red blood cells, prevention of damage to red blood cells by hydrogen peroxide and the like. In addition, it can catalyze the dehydrogenation of glucose -6-phosphate and can be used for enzymatic detection of NAD (or NADP), glucose -6-phosphate, glucose-phosphate isomerase, glucose-phosphate mutase and hexokinase. It is used in combination with hexokinase for enzymatic detection of glucose for biochemical research, commonly used as a diagnostic enzyme in clinic, for glucose analysis, preparation of urine glucose and blood glucose test paper, the stabilizers used in the pharmaceutical industry for vitamin C and B12 preparations can also be used for the desaccharification of proteins and the storage of canned liquor. |
| production method | using yeast as raw material, after EDTA extraction, DEAE fiber column chromatography to remove nucleic acid, then through the phosphoric acid cellulose chromatography, CM-Sephadex chromatography, finally crystallized to obtain the product. |
Last Update：2024-04-09 15:16:53
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View History
ZWISCHENFERMENT TYPE V
2-氟-4-醛基吡啶
2-氨基-3-氯喹喔啉
MALEIC ACID POTASSIUM SALT
肥酸乙酯,己二酸乙酯
叶绿素他达拉非
potassium (bromomethyl)(trifluoro)borate(1-)
6-DIBROMO-4-CHLOROPHENOL
2-氟-4-醛基吡啶
2-氨基-3-氯喹喔啉
MALEIC ACID POTASSIUM SALT
肥酸乙酯,己二酸乙酯
叶绿素他达拉非
potassium (bromomethyl)(trifluoro)borate(1-)
6-DIBROMO-4-CHLOROPHENOL