alpha-Amino-3-(trifluoromethyl)benzeneacetic acid

alpha-Amino-3-(trifluoromethyl)benzeneacetic acid - Names and Identifiers

Name	(2S)-amino[3-(trifluoromethyl)phenyl]ethanoic acid
Synonyms	3-(TrifluoroMethyl)-DL-phenylglycine 3-(TRIFLUOROMETHYL)-DL-PHENYLGLYCINE 2-[3-(Trifluoromethyl)phenyl]glycine 2-(3-TRIFLUOROMETHYL-PHENYL)-DL-GLYCINE amino[3-(trifluoromethyl)phenyl]acetic acid Amino[3-(trifluoromethyl)phenyl]acetic acid Amino-(3-Trifluoromethyl-Phenyl)-Acetic Acid AMINO-(3-TRIFLUOROMETHYL-PHENYL)-ACETIC ACID Benzeneacetic acid, α-amino-3-(trifluoromethyl)- Benzeneacetic acid, a-aMino-3-(trifluoroMethyl)- alpha-Amino-3-(trifluoromethyl)benzeneacetic acid (2S)-amino[3-(trifluoromethyl)phenyl]ethanoicacid (2R)-amino[3-(trifluoromethyl)phenyl]ethanoic acid (2S)-amino[3-(trifluoromethyl)phenyl]ethanoic acid (2R)-2-ammonio-2-[3-(trifluoromethyl)phenyl]acetate Benzeneacetic acid, alpha-amino-3-(trifluoromethyl)-
CAS	242475-26-9
InChI	InChI=1/C9H8F3NO2/c10-9(11,12)6-3-1-2-5(4-6)7(13)8(14)15/h1-4,7H,13H2,(H,14,15)/t7-/m0/s1
InChIKey	SRHNOGZIXICHOU-UHFFFAOYSA-N

alpha-Amino-3-(trifluoromethyl)benzeneacetic acid - Physico-chemical Properties

Molecular Formula	C9H8F3NO2
Molar Mass	219.16
Density	1.415
Boling Point	274℃
Flash Point	120℃
Vapor Presure	0.0027mmHg at 25°C
pKa	1.79±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.504

alpha-Amino-3-(trifluoromethyl)benzeneacetic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany	3
Hazard Class	IRRITANT

alpha-Amino-3-(trifluoromethyl)benzeneacetic acid - Introduction

(2S)-amino[3-(trifluoromethyl)phenyl]ethanoic acid, also known as (2S)-amino[3-(trifluoromethyl)phenyl] acetic acid, it is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: White to almost white crystal
-molecular formula: C9H8F3NO2
-Molecular weight: 219.16g/mol
-Melting Point: about 160-164 degrees Celsius
-Solubility: Soluble in water and some organic solvents, such as methanol, ethanol, dimethyl ether, etc.

Use:
-Pharmaceutical field:(2S)-amino[3-(trifluoromethyl)phenyl]ethanoic acid is a special compound, which is often used as an important raw material for pharmaceutical intermediates and organic synthesis, in particular, it is widely used in peptide or protein drug research.
-Agricultural field: It can also be used as raw materials and intermediates for pesticides.

Method:
The preparation of (2S)-amino[3-(trifluoromethyl)phenyl]ethanoic acid can usually be carried out by the following steps:
1. 3-Trifluoromethylanisole is reacted with dimethylamine to produce 3-trifluoromethylphenylacetamide.
2. 3-trifluoromethylphenylacetamide reacts with glycine under alkaline conditions to generate (2S)-amino[3-(trifluoromethyl)phenyl]ethanoic acid.

Safety Information:
- (2S)-amino[3-(trifluoromethyl)phenyl]ethanoic acid has low toxicity, but it is still necessary to pay attention to safety during operation.
-When in contact with skin or eyes, rinse immediately with water for at least 15 minutes and seek medical help.
-It is recommended to operate in a well-ventilated area or under the use of respiratory protection equipment.
-Store it in a cool and dry place, away from fire and oxidants.
-Follow proper laboratory procedures and personal protective measures when using or handling the compound.

Last Update：2024-04-09 15:17:56