alpha-Benzyl D-glutamate
H-D-Glu-OBzl
CAS: 79338-14-0
Molecular Formula: C12H15NO4
alpha-Benzyl D-glutamate - Names and Identifiers
alpha-Benzyl D-glutamate - Physico-chemical Properties
| Molecular Formula | C12H15NO4 |
| Molar Mass | 237.25 |
| Density | 1.245 |
| Melting Point | 154 °C |
| Boling Point | 416.0±40.0 °C(Predicted) |
| Appearance | Solid |
| Color | Off-white |
| pKa | 4.21±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | -28 ° (C=1, 1mol/L H |
| MDL | MFCD00237065 |
alpha-Benzyl D-glutamate - Reference Information
| uses | 1-benzyl D-glutamic acid ester is an amino acid derivative and can be used as a pharmaceutical intermediate. |
| Preparation | The preparation of 1-benzyl D-glutamic acid ester is prepared by reduction reaction with 1-benzyl D-glutamic acid-benzyl ester as the starting material [1]. Bn is often used to catalyze hydrogen removal, such as H2/20% Pd(OH)2-C, H2/Pd-C, H2/PdCl2, Pd/HCOOH or Pd-C/HCOOH, Pd-C/HCOONH4, Pd-C/NH2NH2 or Pd-C/cyclohexene as hydrogen source transfer hydrogenation, while H2/Pd-C removal is usually slow unless Boc2O is added to promote Bn departure. The synthesis reaction formula of 1-benzyl D-glutamic acid ester is as follows: |
Last Update：2024-04-09 15:16:39
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