alpha-aminodiphenylacetic acid - Names and Identifiers
Name | Alpha,Alpha-Diphenylglycine
|
Synonyms | DIPHENYLGLYCIN 2,2-diphenyl-glycin A,A-DIPHENYLGLYCINE 2,2-Diphenylglycine 2,2-DIPHENYLGLYCINE α,α-Diphenylglycine LABOTEST-BB LT00159592 AMINODIPHENYLACETIC ACID amino(diphenyl)acetic acid ALPHA,ALPHA-DIPHENYLGLYCINE Alpha,Alpha-Diphenylglycine alpha-aminodiphenylacetic acid USP Phenytoin Related Compound A RS
|
CAS | 3060-50-2
|
EINECS | 221-299-6 |
InChI | InChI=1/C14H13NO2/c15-14(13(16)17,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,15H2,(H,16,17) |
InChIKey | YBONNYNNFBAKLI-UHFFFAOYSA-N |
alpha-aminodiphenylacetic acid - Physico-chemical Properties
Molecular Formula | C14H13NO2
|
Molar Mass | 227.26 |
Density | 1.231±0.06 g/cm3 (20 ºC 760 Torr) |
Melting Point | 245-247 °C (dec.) (lit.) |
Boling Point | 368.97°C (rough estimate) |
Flash Point | 185.7°C |
Water Solubility | It is sparingly soluble in water. |
Solubility | DMSO (Slightly, Heated), Methanol (Slightly, Heated) |
Vapor Presure | 1.44E-06mmHg at 25°C |
Appearance | Powder |
Color | White |
pKa | 1.38±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Stability | Hygroscopic |
Refractive Index | 1.5780 (estimate) |
MDL | MFCD00008048 |
alpha-aminodiphenylacetic acid - Risk and Safety
Safety Description | 24/25 - Avoid contact with skin and eyes.
|
WGK Germany | 3 |
RTECS | MC0176000 |
HS Code | 29224999 |
alpha-aminodiphenylacetic acid - Introduction
Alpha,Alpha-Diphenylglycine(Alpha,Alpha-Diphenylglycine) is an organic compound with the chemical formula C14H13NO2. It is a colorless solid, soluble in common organic solvents such as alcohols and ethers.
Alpha,Alpha-Diphenylglycine main use is as a chemical intermediate for organic synthesis reactions. It can be used as a key intermediate in drug synthesis and is widely used in pharmacy. In addition, it can also be used in the production of chemical products such as coatings, dyes and plastics.
Alpha,Alpha-Diphenylglycine can be prepared in a variety of ways. Commonly used method is through the reaction of acetophenone and nitromoform, the formation of nitrate, and then reduction to get Alpha,Alpha-Diphenylglycine. Other methods include synthesis by the reaction of phenol and dichloroacetic acid, or by bromobenzene and glycine.
Regarding safety, Alpha,Alpha-Diphenylglycine is generally stable under normal operating conditions, but contact with strong oxidants and acidic substances should be avoided. Appropriate protective measures should be taken during operation, including wearing protective glasses and gloves to ensure good ventilation. In case of misuse or skin contact, seek medical attention immediately. At the same time, this compound also needs to be stored in a dry, ventilated place, away from open flames and heat sources.
Last Update:2024-04-09 21:54:55