beta-D-Galactopyranoside, (1beta,3beta,25R)-3-hydroxyspirost-5-en-1-yl 6-deoxy-2-O-(6-deoxy-alpha-L-mannopyranosyl)-
Ophiopogonin B
CAS: 38971-41-4
Molecular Formula: C39H62O12
beta-D-Galactopyranoside, (1beta,3beta,25R)-3-hydroxyspirost-5-en-1-yl 6-deoxy-2-O-(6-deoxy-alpha-L-mannopyranosyl)- - Names and Identifiers
| Name | Ophiopogonin B |
| Synonyms | OJV-III Glycoside O-4 Sprengerinin B ophiopogonin B Ophiopogonin B [(25R)-3β-Hydroxyspirost-5-en-1β-yl]6-deoxy-2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-galactopyranoside β-D-Galactopyranoside, (1β,3β,25R)-3-hydroxyspirost-5-en-1-yl 6-deoxy-2-O-(6-deoxy-α-L-mannopyranosyl)- b-D-Galactopyranoside, (1b,3b,25R)-3-hydroxyspirost-5-en-1-yl 6-deoxy-2-O-(6-deoxy-a-L-Mannopyranosyl)- beta-D-Galactopyranoside, (1beta,3beta,25R)-3-hydroxyspirost-5-en-1-yl 6-deoxy-2-O-(6-deoxy-alpha-L-mannopyranosyl)- (1beta,3beta,14xi,25R)-3-hydroxyspirost-5-en-1-yl 6-deoxy-2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside |
| CAS | 38971-41-4 |
| EINECS | 242-826-6 |
| InChI | InChI=1/C39H62O12/c1-17-9-12-39(46-16-17)18(2)28-26(51-39)15-25-23-8-7-21-13-22(40)14-27(38(21,6)24(23)10-11-37(25,28)5)49-36-34(32(44)30(42)20(4)48-36)50-35-33(45)31(43)29(41)19(3)47-35/h7,17-20,22-36,40-45H,8-16H2,1-6H3/t17-,18+,19+,20-,22-,23-,24+,25+,26+,27-,28+,29+,30-,31-,32+,33-,34-,35+,36+,37+,38+,39-/m1/s1 |
beta-D-Galactopyranoside, (1beta,3beta,25R)-3-hydroxyspirost-5-en-1-yl 6-deoxy-2-O-(6-deoxy-alpha-L-mannopyranosyl)- - Physico-chemical Properties
| Molecular Formula | C39H62O12 |
| Molar Mass | 722.9 |
| Density | 1.34±0.1 g/cm3(Predicted) |
| Melting Point | 269-271°C |
| Boling Point | 835.7±65.0 °C(Predicted) |
| Specific Rotation(α) | (Py)-105.5 |
| Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
| Appearance | White crystalline powder |
| pKa | 13.00±0.70(Predicted) |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.604 |
| Physical and Chemical Properties | White amorphous powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Ophiopogon japonicus. |
beta-D-Galactopyranoside, (1beta,3beta,25R)-3-hydroxyspirost-5-en-1-yl 6-deoxy-2-O-(6-deoxy-alpha-L-mannopyranosyl)- - Reference
| Reference Show more | 1. Chen Chen, Feng Jia Yue, Cao Cheng, et al. Study on in vitro activity of polysaccharides and saponins from Ophiopogon japonicus [J]. Food Research and Development, 2018(13). 2. [IF = 4.36] Shuang Yuan et al."The anti-tumor effect of OP-B on ovarian cancer in vitro and in vivo, and its mechanism: An investigation using network pharmacology-based analysis." J Ethnopharmacol. 2022 Jan;283:114706 3. [IF = 2.952] Fang Yuan et al."Ophiopogonin‑B targets PTP1B to inhibit the malignant progression of hepatocellular carcinoma by regulating the PI3K/AKT and AMPK signaling pathways."Mol Med Rep. 2022 Apr;25(4):1-10 4. [IF=4.207] Ziyu Cheng et al."Ophiopogonin B alleviates cisplatin resistance of lung cancer cells by inducing Caspase-1/GSDMD dependent pyroptosis."J Cancer. 2022; 13(2): 715-727 |
beta-D-Galactopyranoside, (1beta,3beta,25R)-3-hydroxyspirost-5-en-1-yl 6-deoxy-2-O-(6-deoxy-alpha-L-mannopyranosyl)- - Reference Information
| introduction | ophiopogon saponin B is a saponin compound extracted from traditional Chinese medicine ophiopogon japonicus, which has anti-tumor, anti-myocardial ischemia, immune regulation and other functions. In the antibacterial experiment, Ophiopogon saponin B can improve the antibacterial performance of clotrimazole against artificially induced drug-resistant Candida albicans. |
| chemical properties | white amorphous powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Ophiopogon japonicus. |
| use | Ophiopogon saponin B has anti-myocardial ischemia, myocardial infarction, immune regulation, lowering blood sugar, and anti-tumor effects. |
Last Update：2024-04-09 21:04:16
Supplier List
Product Name: Ophiopogonin B Visit Supplier Webpage Request for quotation
CAS: 38971-41-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 38971-41-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: Ophiopogonin B Visit Supplier Webpage Request for quotation
CAS: 38971-41-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 38971-41-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History