boronic acid, B-(6-fluoro-2-methyl-3-pyridinyl)-

boronic acid, B-(6-fluoro-2-methyl-3-pyridinyl)- - Names and Identifiers

Name	(6-fluoro-2-methyl-3-pyridyl)boronic acid
Synonyms	2-FLUORO-6-PICOLINE-5-BORONIC ACID 3-Borono-6-fluoro-2-methylpyridine 2-Fluoro-6-methylpyridine-5-boronicacid 6-FLUORO-2-METHYLPYRIDINE-3-BORONIC ACID 2-Fluoro-6-methylpyridine-5-boronic acid 2-FLUORO-6-METHYLPYRIDINE-5-BORONIC ACID (6-FLUORO-2-METHYL-3-PYRIDYL)BORONIC ACID (6-fluoro-2-methyl-3-pyridyl)boronic acid (6-fluoro-2-methylpyridin-3-yl)boronic acid (6-FLUORO-2-METHYLPYRIDIN-3-YL)BORONIC ACID (2-Fluoro-6-methylpyridin-5-yl)boronic acid Boronic acid,B-(6-fluoro-2-Methyl-3-pyridinyl) boronic acid, B-(6-fluoro-2-methyl-3-pyridinyl)-
CAS	904326-91-6
InChI	InChI=1/C6H7BFNO2/c1-4-5(7(10)11)2-3-6(8)9-4/h2-3,10-11H,1H3

boronic acid, B-(6-fluoro-2-methyl-3-pyridinyl)- - Physico-chemical Properties

Molecular Formula	C6H7BFNO2
Molar Mass	154.93
Density	1.28±0.1 g/cm3(Predicted)
Boling Point	308.0±52.0 °C(Predicted)
Flash Point	140.1°C
Vapor Presure	0.000303mmHg at 25°C
pKa	7.05±0.58(Predicted)
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.504

boronic acid, B-(6-fluoro-2-methyl-3-pyridinyl)- - Introduction

boronic acid, also known as boronic acid, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: White solid
-Molecular formula: C7H8BFO2
-Solubility: Soluble in many organic solvents, such as ethanol, dimethyl sulfoxide and dimethylformamide
-Melting point: approximately 140-145°C

Use: -(br>) boronic acid is commonly used in metal-catalyzed reactions in organic synthesis, especially phenylboronic acid reactions. It can be used as an important intermediate in organic synthesis for the synthesis of various organic compounds, such as heterocyclic compounds, heterocyclic lithium salts and heterocyclic alkenes.

Method:
- (No) boronic acid can be synthesized by a variety of methods, the common method is obtained by the reaction of 2-fluoro-5-boronic acid pyridine and methyl fluoride. This reaction is usually carried out under an inert atmosphere using a base as a catalyst.
-In addition, it can also be synthesized by other methods, such as the reaction of 2-fluoro-5-boronic acid pyridine and methyl magnesium bromide.

Safety Information:
-boronic acid is stable under normal conditions.
-When handling, appropriate personal protective measures should be taken, such as wearing gloves and safety glasses.
-This compound may absorb moisture in the air, so it should be stored in a dry place to avoid moisture.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.

Please note that the above information is for reference. Before actually using the compound, please make sure to read the corresponding safety materials and synthetic methods carefully, and follow the laboratory safety procedures.

Last Update：2024-04-10 22:29:15