bromo(1-phenylethyl)zinc
bromo(1-phenylethyl)zinc
CAS: 85459-20-7
Molecular Formula: C8H9BrZn
bromo(1-phenylethyl)zinc - Names and Identifiers
| Name | bromo(1-phenylethyl)zinc |
| Synonyms | bromo(1-phenylethyl)zinc A-METHYLBENZYLZINC BROMIDE ALPHA-METHYLBENZYLZINC BROMIDE alpha-Methylbenzylzinc chloride α-methylbenzylzinc bromide solution α-Methylbenzylzinc bromide, 0.5 M in THF α-Methylbenzylzinc bromide solution 0.5M in THF ALPHA-METHYLBENZYLZINC BROMIDE, 0.5M SOL UTION IN TETRAHYDROFURAN |
| CAS | 85459-20-7 |
| InChI | InChI=1/C8H9.BrH.Zn/c1-2-8-6-4-3-5-7-8;;/h2-7H,1H3;1H;/q;;+1/p-1/rC8H9BrZn/c1-7(10-9)8-5-3-2-4-6-8/h2-7H,1H3 |
bromo(1-phenylethyl)zinc - Physico-chemical Properties
| Molecular Formula | C8H9BrZn |
| Molar Mass | 250.44 |
| Density | 0.965g/mLat 25°C |
| Flash Point | 1°F |
| Water Solubility | Reacts with water. |
| Appearance | Liquid |
| Color | Yellow to brown to black |
| Exposure Limit | ACGIH: TWA 50 ppm; STEL 100 ppm (Skin)OSHA: TWA 200 ppm(590 mg/m3)NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3) |
| Storage Condition | 2-8°C |
| Sensitive | Air Sensitive |
bromo(1-phenylethyl)zinc - Risk and Safety
| Risk Codes | R14 - Reacts violently with water R19 - May form explosive peroxides R22 - Harmful if swallowed R36/38 - Irritating to eyes and skin. R40 - Limited evidence of a carcinogenic effect R36/37 - Irritating to eyes and respiratory system. R11 - Highly Flammable |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S33 - Take precautionary measures against static discharges. S36 - Wear suitable protective clothing. S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | UN 2056 3/PG 2 |
| WGK Germany | 1 |
| HS Code | 29319090 |
| Hazard Class | 4.3 |
bromo(1-phenylethyl)zinc - Introduction
Bromo (1-phenylethyl)zinc is an organic compound with the chemical formula C8H9BrZn. It is a white to off-white solid, soluble in organic solvents such as diethyl ether and tetrahydrofuran. It is a reactive compound that can be used as an important reagent in organic synthesis.
bromo(1-phenylethyl)zinc is mainly used for the synthesis of benzyl. Common reactions include the synthesis of aryl boronic acid and Suzuki coupling reaction. It can also be used in the synthesis of phenyl, benzyl and substituted phenyl organic compounds.
The preparation of bromo(1-phenylethyl)zinc is usually obtained by reacting benzyl bromide as a raw material with zinc iodide. The reaction process requires an inert atmosphere and the addition of a complexing agent such as dimethyl sulfoxide (DMSO). The preparation method is relatively simple and the yield is high.
Regarding safety information, bromo(1-phenylethyl)zinc is an organometallic compound, which has certain safety risks. It has an irritating effect on the eyes, skin and respiratory tract, so care should be taken to avoid contact with skin and eyes when using it. At the same time, it is also flammable and needs to be stored in a cool, dry place, away from fire and oxidants. For the specific handling and storage of this compound, please follow the operating specifications and safety manuals of the relevant chemical laboratory.
bromo(1-phenylethyl)zinc is mainly used for the synthesis of benzyl. Common reactions include the synthesis of aryl boronic acid and Suzuki coupling reaction. It can also be used in the synthesis of phenyl, benzyl and substituted phenyl organic compounds.
The preparation of bromo(1-phenylethyl)zinc is usually obtained by reacting benzyl bromide as a raw material with zinc iodide. The reaction process requires an inert atmosphere and the addition of a complexing agent such as dimethyl sulfoxide (DMSO). The preparation method is relatively simple and the yield is high.
Regarding safety information, bromo(1-phenylethyl)zinc is an organometallic compound, which has certain safety risks. It has an irritating effect on the eyes, skin and respiratory tract, so care should be taken to avoid contact with skin and eyes when using it. At the same time, it is also flammable and needs to be stored in a cool, dry place, away from fire and oxidants. For the specific handling and storage of this compound, please follow the operating specifications and safety manuals of the relevant chemical laboratory.
Last Update：2024-04-10 22:29:15
