cyclopropyl(thiophen-2-yl)methanone - Names and Identifiers
cyclopropyl(thiophen-2-yl)methanone - Physico-chemical Properties
Molecular Formula | C8H8OS
|
Molar Mass | 152.21 |
Density | 1.17g/mLat 25°C(lit.) |
Boling Point | 120 °C / 3mmHg |
Flash Point | 198°F |
Vapor Presure | 0.0092mmHg at 25°C |
Appearance | Liquid |
Color | Colorless to Light yellow to Light orange |
Storage Condition | Keep in dark place,Sealed in dry,2-8°C |
Refractive Index | n20/D 1.584(lit.) |
MDL | MFCD00005427 |
cyclopropyl(thiophen-2-yl)methanone - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
|
WGK Germany | 3 |
HS Code | 29349990 |
cyclopropyl(thiophen-2-yl)methanone - Introduction
Cyclopropyl 2-thienyl ketone is an organic compound with the chemical formula C9H8OS. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless liquid or solid
-Melting point: about -25 ℃
-Boiling point: about 236-240 ℃
-Density: about 1.22g/cm³
-Solubility: Slightly soluble in water, soluble in organic solvents
Use:
Cyclopropyl 2-thienyl ketone is often used as an intermediate and reagent in organic synthesis. Specific applications include:
-for the preparation of drugs
-Used as synthetic intermediates for pesticides and insecticides
-For organic synthesis reactions, such as acylation, substitution reactions, etc.
Preparation Method:
Cyclopropyl 2-thienyl ketone can be prepared by the following reaction pathways:
1. Cyclopropylamine and 2-chlorothiophene react to generate 2-thiophenyl cyclopropylamine.
2. 2-thiophenylcyclopropylamine is further treated with a ketonizing agent (such as sodium ketonate) to obtain the Cyclopropyl 2-thienyl ketone.
Safety Information:
Cyclopropyl 2-thienyl ketone is relatively safe under proper use and storage conditions. However, as an organic compound, it should be regarded as a potentially hazardous substance and needs to follow safe handling measures to protect individuals and the environment. When handling, avoid inhalation of vapors, contact with skin and eyes. At the same time, store it in a sealed container, away from fire and oxidizing agents. In case of accidental contact or misuse, seek medical help immediately. Be sure to consult the safety data form for the compound in detail before use and follow the relevant safety instructions.
Last Update:2024-04-09 21:11:58