diethyl 1-benzyl-3,4-difluoropyrrolidine-3,4-dicarboxylate - Names and Identifiers
diethyl 1-benzyl-3,4-difluoropyrrolidine-3,4-dicarboxylate - Introduction
diethyl 1-benzyl-3,4-difluoropyrrolidine-3,4-dicarboxylate is an organic compound containing a pyrrole ring and a dicarboxylic ester group in its structure. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless or light yellow liquid
-Molecular formula: C14H18F2N2O4
-Molecular weight: 322.30g/mol
-Melting point: 40-43 ° C
-Boiling Point: 311-313 ° C
-Density: 1.221 g/ml at 25 ° C
-Solubility: Soluble in common organic solvents such as ethanol, chloroform and dichloromethane
Use:
diethyl 1-benzyl-3,4-difluoropyrrolidine-3,4-dicarboxylate is often used as an important intermediate in organic synthesis. It can be used to synthesize drugs, pesticides and other biologically active compounds. Because of its special structure and chemical properties, it has a wide range of applications in the fields of medicinal chemistry, pesticides and materials science.
Method:
The preparation of the compound can usually be carried out by the following steps:
1.1-ethyl-3, 4-difluoropyrrolidine (diethyl 1-benzyl-3,4-difluoropyrrolidine) was reacted with isopropyl bromide to produce 1-ethyl-3, 4-difluoropyrrolidine-3,4-dione (diethyl 1-benzyl-3,4-difluoropyrrolidine-3,4-dione).
2.1-ethyl -3,4-difluoropyrrolidine-3, 4-dione is reacted with acetaldehyde to generate diethyl 1-benzyl-3,4-difluoropyrrolidine-3,4-dicarboxylate.
Safety Information:
Last Update：2024-04-09 02:00:51