diethyl 5-amino-3-methylthiophene-2,4-dicarboxylate

diethyl 5-amino-3-methylthiophene-2,4-dicarboxylate - Names and Identifiers

Name	Diethyl 5-amino-3-methyl-2,4-thiophenedicarboxylate
Synonyms	AURORA 879 ASISCHEM S46503 ART-CHEM-BB B000492 Diethyl 5-amino-3-methyl-2,4-thiophenedicarboxylate diethyl 5-amino-3-methylthiophene-2,4-dicarboxylate 5-Amino-3-methyl-2,4-thiophenedicarboxilic acid diethyl ester
CAS	4815-30-9
EINECS	225-388-0
InChI	InChI=1/C11H15NO4S/c1-4-15-10(13)7-6(3)8(17-9(7)12)11(14)16-5-2/h4-5,12H2,1-3H3

diethyl 5-amino-3-methylthiophene-2,4-dicarboxylate - Physico-chemical Properties

Molecular Formula	C11H15NO4S
Molar Mass	257.31
Density	1.247g/cm³
Melting Point	103-108℃
Boling Point	372.6°C at 760 mmHg
Flash Point	179.1°C
Vapor Presure	9.51E-06mmHg at 25°C
Appearance	Form Crystalline Powder, color Slightly yellow to beige-yellow
pKa	-0.53±0.10(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.558
MDL	MFCD00005450
Use	Use 5-amino -3-methyl -2, 4-thiophenol dicarboxylic acid Diethyl ester can be used as a pharmaceutical intermediate.

diethyl 5-amino-3-methylthiophene-2,4-dicarboxylate - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29349990
Hazard Class	IRRITANT

diethyl 5-amino-3-methylthiophene-2,4-dicarboxylate - Upstream Downstream Industry

Raw Materials

Ethyl 3-oxobutanoate sodium salt
Ethyl cyanoacetate
Ethyl acetoacetate

diethyl 5-amino-3-methylthiophene-2,4-dicarboxylate - Introduction

Diethyl 5-amino-3-methyl-2,4-thiophenedicarboxylate is an organic compound with the chemical formula C12H15NO4S. The following is a description of some of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless to light yellow liquid
-Melting point: no clear melting point
-Boiling point: about 325°C
-Density: Approximately 1.19 g/mL
-Solubility: Soluble in ethanol, ether and dichloromethane

Use:
- Diethyl 5-amino-3-methyl-2,4-thiophenedicarboxylate can be used as an intermediate in organic synthesis.
-It can be used in the field of medicine for the synthesis of new drugs or drug precursors.
-In the field of pesticides, it can also be used as a pesticide intermediate.

Preparation Method:
- Diethyl 5-amino-3-methyl-2,4-thiophenedicarboxylate is usually prepared by esterification of 3,5-dimethylthiophene -2, 4-dione with diethoxymethylthiophosphate.

Safety Information:
- Diethyl 5-amino-3-methyl-2,4-thiophenedicarboxylate is generally relatively safe under correct use and storage conditions.
-As a chemical, it may have an irritating effect on the skin, eyes and respiratory tract, so direct exposure should be avoided during contact.
-When using or handling the compound, please follow the correct laboratory safety procedures and wear appropriate personal protective equipment, such as laboratory gloves and eye protection equipment.

Please note that any chemical should be handled under appropriate laboratory conditions and follow relevant safe operating procedures.

Last Update：2024-04-09 20:49:11