ethyl 2-hydrazino-4-methylpyrimidine-5-carboxylate

ethyl 2-hydrazino-4-methylpyrimidine-5-carboxylate - Names and Identifiers

Name	ethyl 2-hydrazino-4-methylpyrimidine-5-carboxylate
Synonyms	Ethyl 2-hydrazino-4-methylpyrimidine-5-carboxylate ethyl 2-hydrazino-4-methylpyrimidine-5-carboxylate ETHYL 2-HYDRAZINYL-4-METHYLPYRIMIDINE-5-CARBOXYLATE Ethyl 2-hydrazinyl-4-methylpyrimidine-5-carboxylate 5-Pyrimidinecarboxylic acid, 2-hydrazino-4-methyl-, ethyl ester 5-Pyrimidinecarboxylic acid, 2-hydrazinyl-4-methyl-, ethyl ester
CAS	66373-46-4

ethyl 2-hydrazino-4-methylpyrimidine-5-carboxylate - Physico-chemical Properties

Molecular Formula	C8H12N4O2
Molar Mass	196.21
Density	1.34±0.1 g/cm3(Predicted)
Melting Point	173-174 °C
Boling Point	331.9±52.0 °C(Predicted)
pKa	5.47±0.40(Predicted)

ethyl 2-hydrazino-4-methylpyrimidine-5-carboxylate - Risk and Safety

Risk Codes	20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description	S24/25 - Avoid contact with skin and eyes. S36/37 - Wear suitable protective clothing and gloves.
HS Code	29335990

ethyl 2-hydrazino-4-methylpyrimidine-5-carboxylate - Introduction

Ethyl, also known as ethyl 2-hydrazino-4-methylpyrimidine-5-carboxylate, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White crystalline solid
-Molecular formula: C8H11N5O2
-Molecular weight: 209.21g/mol
-Melting Point: 206-208°C
-Solubility: Soluble in a few organic solvents such as ethanol, ether and chloroform

Use:
- ethyl l can be used as an intermediate for the synthesis of other organic compounds.
-It can be used in the synthesis of pyrimidine natural products, pesticides and synthetic drugs in the field of medicine, with potential biological activity.

Preparation Method:
ethyl l can be synthesized by the following steps:
1. First, ethyl bromoacetate was reacted with sodium tert-butoxide to obtain tert-butyl ethyl acetate.
2. Next, tert-butyl ethyl acetate is reacted with hydrazine to produce hydrazine ethyl acetate.
3. Finally, ethyl hydrazine acetate is reacted with acetic anhydride and silver formate to obtain ethyl l.

Safety Information:
- ethyl l is an organic compound and should be handled in accordance with safe operating procedures.
-It may have an irritating effect on the eyes, skin and respiratory tract, so personal protective equipment such as safety glasses, gloves and a protective mask should be worn during operation.
-When stored, the compound should be kept in a dry, cool and well-ventilated place, away from fire and oxidizing agents.
-Observe safety practices when using and handling the compound, such as avoiding inhalation, contact with skin and mouth, and regular hand washing and cleaning of the work area.

Last Update：2024-04-09 21:01:54