ethyl trans-2-(2-(trifluoromethoxy)phenyl)cyclopropane-1-carboxylate - Names and Identifiers
ethyl trans-2-(2-(trifluoromethoxy)phenyl)cyclopropane-1-carboxylate - Introduction
ethyl trans-2-(2-(trifluoromethoxy)phenyl), also known as ethyl acetate, is a chemical substance with the chemical formula C14H13F3O3.
Nature:
-Appearance: colorless liquid
-Boiling Point: 137-138 ° C
-Density: 1.25 g/mL
-Melting point:-1 ° C
Use:
Ethyl acetate is commonly used as an intermediate and solvent in organic synthesis, and has a wide range of applications, including:
-Drugs: Used to synthesize drugs, such as anti-cancer drugs and anti-inflammatory drugs.
-Agriculture: Can be used to prepare insecticides, fungicides and herbicides.
-Spices and Fragrances: Can be used to synthesize fragrance and fragrance ingredients.
-Paint and solvent: as a solvent, used in paint, glue and cleaning agent.
Method:
The preparation of ethyl acetate is usually carried out by esterification reaction, the specific steps are as follows:
1. Ethanol is reacted with trans-2-(2-(trifluoromethoxy) phenyl) cyclopropane -1-carboxylic acid.
2. The reaction is carried out under acidic conditions, and sulfuric acid or phosphoric acid is usually used as a catalyst.
3. The reaction produces ethyl acetate.
4. Finally, pure ethyl acetate was obtained by distillation and purification steps.
Safety Information:
The use of ethyl acetate in the process need to pay attention to the following safety matters:
-Ethyl acetate is a flammable liquid, and open flames and high temperatures should be avoided during storage and use.
-Exposure to ethyl acetate may cause irritation to the eyes, skin, and respiratory system. Wear appropriate personal protective equipment such as gloves, goggles, and protective masks.
-Avoid prolonged or heavy exposure to ethyl acetate to avoid poisoning.
-When operating ethyl acetate, it should be carried out in a well-ventilated environment to prevent the accumulation of gas in the room.
-Disposal of ethyl acetate waste in accordance with local environmental regulations.
Last Update：2024-04-09 19:05:55