ethyl-2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-carboxylate - Names and Identifiers
ethyl-2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-carboxylate - Physico-chemical Properties
Molecular Formula | C21H18FNO2
|
Molar Mass | 335.37 |
Density | 1.248 |
Melting Point | 74-76°C |
Boling Point | 469.2±45.0 °C(Predicted) |
Flash Point | 237.545°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 3.54±0.50(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.627 |
ethyl-2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-carboxylate - Introduction
Ethyl 2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-carboxylate, abbreviated as CFPQL, is an organic compound. The following is an introduction to its nature, use, formulation and safety information:
Nature:
1. Appearance: Ethyl 2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-carboxylate is a colorless to pale yellow liquid.
2. Melting Point: About -30 ° C.
3. Boiling Point: about 370 ° C.
4. Solubility: Soluble in many organic solvents, such as ethanol, dimethyl sulfoxide and dichloromethane.
Use:
Ethyl 2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-carboxylate has important application value in organic synthesis and is often used to synthesize pesticides and pharmaceutical intermediates. It can also be used in organic chemistry research and laboratory synthesis reactions.
Method:
The synthesis of Ethyl 2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-carboxylate is usually obtained by a multi-step reaction. A common synthesis method is to react 4-fluorobenzoic acid with terephthalonitrile in an ammonia atmosphere to produce 2-cyclopropyl-4-(4-fluorophenyl)-Quinoline -3-carboxylic acid, and then esterified with ethanol to produce the target product.
Safety Information:
1. Ethyl 2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-carboxylate is an organic compound. Please pay attention to personal protective measures during use, such as wearing gloves and protective glasses.
2. Avoid contact with skin and eyes, if contact, should immediately rinse with plenty of water.
3. During storage and use, avoid contact with oxidants to avoid dangerous chemical reactions.
4. Please pay attention to ventilation during operation and avoid inhaling its steam.
5. If swallowed or taken by mistake, please seek medical attention immediately and bring the packaging container or label.
Last Update:2024-04-09 15:17:52