glucose 6-(disodium phosphate)
D-glucose 6-phosphate disodiumsalt dihydrate
CAS: 3671-99-6
Molecular Formula: C6H14NaO9P
glucose 6-(disodium phosphate) - Names and Identifiers
| Name | D-glucose 6-phosphate disodiumsalt dihydrate |
| Synonyms | glucose 6-(disodium phosphate) disodium 6-O-phosphonato-L-idose Glucose-6-phosphate, Disodium Salt D-Glucose-6-phosphate disodium salt D-Glucose 6-phosphoric acid disodium salt D-Glucose 6-phosphate dihydrate disodium D-glucose 6-phosphate disodiumsalt dihydrate D-GLUCOSE-6-PHOSPHATE DISODIUM SALT extrapure D-Glucose 6-phosphate hydrate disodium salt disodium 6-O-phosphonato-D-glucopyranose hydrate G-6-P-Na2 salt, Robison ester disodium salt D-GLUCOSE 6-PHOSPHATE DISODIUM*HYDRATE S IGMA GRADE D-Glucose 6-Phosphate Disodium Salt Hydrate(G-6-P disodium [(2S,3R,4S,5R)-2,3,4,5-tetrahydroxy-6-keto-hexyl] phosphate |
| CAS | 3671-99-6 |
| EINECS | 222-938-1 |
| InChI | InChI=1/C6H13O9P.2Na.H2O/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6?;;;/m1.../s1 |
| InChIKey | CHIBNKGHYAQTQY-DUMCKRSRSA-L |
glucose 6-(disodium phosphate) - Physico-chemical Properties
| Molecular Formula | C6H14NaO9P |
| Molar Mass | 284.13 |
| Water Solubility | Soluble in water |
| Solubility | Soluble in water (100 mg/ml), and dilute buffer. |
| Appearance | Powder |
| Color | White to Off-white |
| BRN | 5199009 |
| Storage Condition | -20°C |
| Sensitive | Easily absorbing moisture |
| MDL | MFCD00150940 |
| Physical and Chemical Properties | D-glucose -6-phosphate disodium is an organic substance, which is mainly used in biochemical research, the determination of glucose -6-phosphate dehydrogenase substrate. |
| Use | An inhibitor of HXK (hexokinase). |
| In vitro study | This dianion is very common in cells as the majority of glucose entering a cell will become phosphorylated in this way. |
glucose 6-(disodium phosphate) - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 3-10 |
| TSCA | Yes |
| HS Code | 29400000 |
glucose 6-(disodium phosphate) - Reference
| Reference Show more | 1. [IF=1.908] Yan Liu et al."Study on the pharmacokinetics of deoxyschizandrin and schizandrin in combination with epigallocatechin gallate, a component of green tea, in rats."Xenobiotica. 2018;48(4):412-421 2. [IF=7.46] Dongxue Sun et al."Coupling p-Hydroxybenzoate Hydroaxylase with the Photoresponsive Nanozyme for Universal Dehydrogenase-Based Bioassays."Sensor Actuat B-Chem. 2021 Jan;327:128859 3. [IF=4.155] Siqi Zhang et al."Step-wise immobilization of multi-enzymes by zirconium-based coordination polymer in situ self-assembly and specific absorption."J Inorg Biochem. 2020 Jul;208:111093 |
glucose 6-(disodium phosphate) - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| safety instructions | if D-glucose -6-disodium phosphate is inhaled, please move the patient to fresh air. If the skin is in contact with the skin, remove the contaminated clothes, rinse the skin thoroughly with soapy water and clear water, and see a doctor if you feel uncomfortable. If the eyes are in contact with clear eyes, separate the eyelids and rinse with flowing water or normal saline, and seek medical treatment immediately; if ingested, gargle immediately, forbid vomiting, should seek medical treatment immediately. |
| application | D-glucose -6-phosphate disodium is mainly used for biochemical research, for example, it can be used to determine the inhibitory effect of rutaecarpine on liver metabolism in vitro of rats with five kinds of coptis alkaloids. D-glucose -6-phosphate disodium is mainly used for biochemical research. The substrate of glucose -6-phosphate dehydrogenase was determined. For example, it is used to identify metabolites of epi-berberine in vitro rat liver microsomal incubation. |
| Biological activity | D-Glucose-6-phosphate disodium salt is called glucose 6-phosphate, which is a molecule generated after glucose is phosphorylated (in carbon No. 6). It is a common molecule in biological cells and participates in biochemical pathways such as pentose phosphate pathway and glycolysis. |
Last Update：2024-04-09 21:11:58
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