Name | Glycylglycine |
Synonyms | Gly-Gly GLY-GLY DIGLYCINE Diglycine GLY-GLY-OH H-Gly-Gly-OH H-GLY-GLY-OH Glycylglycine GLYCYLGLYCINE N-Glycyl-Glycine gly-gly free base Glycylglycine, Free Base Glycyl-glycine,(Diglycine) [(Aminoacetyl)amino]acetic acid (2-Amino-acetylamino)-aceticacid |
CAS | 556-50-3 |
EINECS | 209-127-8 |
InChI | InChI=1/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9) |
InChIKey | YMAWOPBAYDPSLA-UHFFFAOYSA-N |
Molecular Formula | C4H8N2O3 |
Molar Mass | 132.12 |
Density | 1.5851 (rough estimate) |
Melting Point | 220-240°C (dec.) |
Boling Point | 267.18°C (rough estimate) |
Water Solubility | SOLUBLE IN HOT WATER |
Solubility | Easily soluble in water, slightly soluble in ethanol, insoluble in ether. |
Vapor Presure | 0.058Pa at 20-50℃ |
Appearance | White crystal |
Color | White |
Maximum wavelength(λmax) | ['λ: 260 nm Amax: 0.075', , 'λ: 280 nm Amax: 0.072'] |
Merck | 14,4503 |
BRN | 1765223 |
pKa | 3.139(at 25℃) |
PH | 4.5-6.0 (20℃, 1M in H2O) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Stability | Stable. Incompatible with strong oxidizing agents. |
Sensitive | Easily absorbing moisture |
Refractive Index | 1.4880 (estimate) |
MDL | MFCD00008130 |
Physical and Chemical Properties | Character: white flaky crystal, glossy. soluble in water, slightly soluble in ethanol, insoluble in ether. |
Use | Used as a Biochemical reagent |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36 - Irritating to the eyes |
Safety Description | S24/25 - Avoid contact with skin and eyes. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10 |
TSCA | Yes |
HS Code | 29241900 |
pH range of acid-base indicator discoloration | 7.5 - 8.9 |
LogP | -0.92 at 25℃ and pH6 |
NIST chemical information | information provided by: webbook.nist.gov (external link) |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
properties | diglycinin (L-Glycylglycine) is a white leaf-like crystal with a melting point of 260-262 ℃ (decomposition). 25 ° C water solubility of 13.4g/100mL, soluble in hot water, insoluble in alcohol, insoluble in ether. |
Application | glycopeptide is a biochemical reagent, it is used as a stabilizer for blood preservation and protein drug cytochrome C injection in biological research and medicine, and can be used to determine the substrate of diglycopeptide dipeptidase and synthesize polypeptides. And as a short peptide, the interaction between diglycyl peptide and transition metal plays a key role in many fields such as bioengineering and pharmaceutical chemistry. |
purpose | This product is a biochemical reagent, it is used as a stabilizer for blood preservation and protein drug cytochrome C injection in biological research and medicine. used as Biochemical reagent |
production method | is obtained by condensation and decomposition of glycine. The glycine and ethylenediamine were mixed at 1:56, stirred at 174-176 ℃ for 50min, then placed in the ice chamber for 20h, filtered and heated with water to dissolve glycyl anhydride, cooling gave light brown crystals, which were filtered and washed with methanol to give the crude product. The crude product by water recrystallization, sterilization and drying is the finished product. |