Molecular Formula | C20H22O4 |
Molar Mass | 326.39 |
Boling Point | 452.0±45.0 °C at 760 mmHg |
Solubility | Insuluble (9.5E-3 g/L) (25 °C) |
Appearance | Powder |
Storage Condition | 2-8℃ |
In vitro study | Licarin A is found in plants such as Aristolochia taliscana , Machilus thunbergii and Myristica fragrans , which are used as spices and in folk medicines for nervous and digestive disorders. Licarin A also exhibits anti-inflammatory effects. Licarin A (5-20 μM) reduces TNF-α and prostaglandin D2 (PGD2) secretion via the inhibition of PKCα/βII and p38 MAPK pathways. Licarin A treatment tends to reduce phosphorylated PKCα/βII and p38 MAPK protein levels. |
Use | likalin A, also known as likalin A, is A lignan component in saururus chinensis. Saurus chinensis; Scientific name: Saurus chinensis (Lur.). The whole plant medicinal, internal treatment of urinary tract infection, urinary calculi, beriberi edema and nutritional edema; External treatment of acne, eczema and other skin. |
biological activity | Licarin A (( )-Licarin A), can be isolated from A variety of plants, significantly reduced dinitrophenylhydrazine-human serum albumin (DNP-HSA) stimulated RBL-2H3 cells. Has anti-allergic effect. Licarin A reduced TNF-α and PGD2 production, and COX-2 expression. |