maleimidoacetic acid N-*hydroxysuccinimide ester
maleimidoacetic acid N-*hydroxysuccinimide ester
CAS: 55750-61-3
Molecular Formula: C10H8N2O6
maleimidoacetic acid N-*hydroxysuccinimide ester - Names and Identifiers
| Name | maleimidoacetic acid N-*hydroxysuccinimide ester |
| Synonyms | MaleiMidoacetic a-Maleimidoacetic acid-NHS N-SUCCINIMIDYL MALEIMIDOACETATE N-(α-MaleiMidoacetoxy)succiMide N-(α-Maleimidoacetoxy)succinimide Ester(AMAS) MALEIMIDOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER maleimidoacetic acid N-*hydroxysuccinimide ester 1-{2-[(2,5-dioxopyrrolidin-1-yl)oxy]-2-oxoethyl}-1H-pyrrole-2,5-dione 1-[2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-1H-pyrrole-2,5-dione 1H-Pyrrole-2,5-dione, 1-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]- |
| CAS | 55750-61-3 |
| InChI | InChI=1/C10H8N2O6/c13-6-1-2-7(14)11(6)5-10(17)18-12-8(15)3-4-9(12)16/h1-2H,3-5H2 |
| InChIKey | TYKASZBHFXBROF-UHFFFAOYSA-N |
maleimidoacetic acid N-*hydroxysuccinimide ester - Physico-chemical Properties
| Molecular Formula | C10H8N2O6 |
| Molar Mass | 252.18 |
| Density | 1.63±0.1 g/cm3(Predicted) |
| Melting Point | 174-175°C |
| Boling Point | 430.1±47.0 °C(Predicted) |
| Flash Point | 213.9°C |
| Solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated, Sonicat |
| Vapor Presure | 1.33E-07mmHg at 25°C |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | -2.69±0.20(Predicted) |
| Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
| Refractive Index | 1.619 |
| In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
maleimidoacetic acid N-*hydroxysuccinimide ester - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29280000 |
maleimidoacetic acid N-*hydroxysuccinimide ester - Reference Information
| biological activity | AMAS is a non-cleavable, heterobifunctional crosslinkers with NHS Ester and maleimide groups, which allow covalent binding of amine and thiol-containing molecules, are commonly used linkers for ADCs. |
Last Update：2024-04-10 22:29:15
Supplier List
Product Name: Maleimidoacetic Acid N-Hydroxysuccinimide Ester Visit Supplier Webpage Request for quotation
CAS: 55750-61-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 55750-61-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: Maleimidoacetic Acid N-Hydroxysuccinimide Ester Visit Supplier Webpage Request for quotation
CAS: 55750-61-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 55750-61-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History