methyl 2-methyl-2-(4-(trifluoromethyl)pyridin-2-yl)propanoate - Names and Identifiers
methyl 2-methyl-2-(4-(trifluoromethyl)pyridin-2-yl)propanoate - Introduction
methyl 2-methyl 2-(4-(trifluoromethyl)pyridin-2-yl)propanoate is an organic compound with the chemical formula C12H12F3NO2.
Nature:
-Appearance: colorless liquid
-Melting point:-20 ° C
-Boiling point: 135-136 ° C
-Density: 1.268g/cm³
Use:
methyl 2-methyl-2-(4-(trifluoromethyl)pyridin-2-yl)propanoate is commonly used as a reaction reagent in organic synthesis. As a substrate and intermediate in Organic Synthesis (especially for heterocyclic compounds), it can be used to synthesize a variety of drugs, pesticides and functional materials.
Method:
methyl 2-methyl-2-(4-(trifluoromethyl)pyridin-2-yl)propanoate can be synthesized by the following steps:
1. Under basic conditions, methyl 3-cyanopropionate is reacted with 2-(4-trifluoromethylpyridin-2-yl) ethanol to give 2-(4-trifluoromethylpyridin-2-yl) methyl propionate.
2. Then, this product is methylesterized under acidic conditions to obtain the target product methyl 2-methyl-2-(4-(trifluoromethyl)pyridin-2-yl)propanoate.
Safety Information:
methyl 2-methyl-2-(4-(trifluoromethyl)pyridin-2-yl)propanoate is relatively stable under correct use and storage. However, it is a flammable liquid and irritating, so direct contact with the skin, eyes and respiratory tract should be avoided. It is necessary to take appropriate protective measures during use and ensure that it is operated in a well-ventilated place.
Last Update：2024-04-09 02:00:52