methyl 4-aminopicolinate

methyl 4-aminopicolinate - Names and Identifiers

Name	Methyl 4-aminopyridine-2-carboxylate
Synonyms	CHEMPACIFIC 38133 methyl 4-aminopicolinate Methyl 4-aminopyridine-2-carboxylate Methyl 4-amino-2-pyridinecarboxylate METHYL 4-AMINO-PYRIDINE-2-CARBOXYLATE METHYL 4-AMINO-PYRIDINE-2-CARBOXYLIC ACID 4-Aminopyridine-2-carboxylic acid methyl ester 4-AMINO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER 4-Amino-2-pyridine carboxylic acid methyl ester 2-Pyridinecarboxylicacid,4-amino-,methylester(9CI)
CAS	71469-93-7
InChI	InChI=1/C7H8N2O2/c1-11-7(10)6-4-5(8)2-3-9-6/h2-4H,1H3,(H2,8,9)

methyl 4-aminopicolinate - Physico-chemical Properties

Molecular Formula	C7H8N2O2
Molar Mass	152.15
Density	1.238±0.06 g/cm3(Predicted)
Melting Point	129-130°
Boling Point	333.7±22.0 °C(Predicted)
Flash Point	155.6°C
Vapor Presure	0.000135mmHg at 25°C
Appearance	powder to crystal
Color	White to Light yellow
pKa	4.35±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.57

methyl 4-aminopicolinate - Risk and Safety

UN IDs	UN2811
Hazard Class	IRRITANT

methyl 4-aminopicolinate - Introduction

Methyl 4-aminopyridine-2-carboxylate(Methyl 4-aminopyridine-2-carboxylate) is an organic compound with the chemical formula C7H8N2O2.

Nature:
-Appearance: colorless crystal or crystalline powder state;
-melting point: 117-119 degrees Celsius;
-Boiling point: 315 degrees Celsius;
-Solubility: Soluble in ethanol, ether and chloroform, slightly soluble in water.

Use:
-Commonly used as an intermediate in organic synthesis;
-can be used for the synthesis of pyridine or related compounds.

Preparation Method:
The preparation method of Methyl 4-aminopyridine-2-carboxylate is more complicated. A common preparation method is as follows:
1. reacting 2-chloropyridine with methanol to generate 2-chloropyridine methanol;
2. treating 2-chloropyridine methanol with sodium oxide (NaOH) to obtain 4-chloro-2-aminopyridine;
3. reacting 4-chloro-2-aminopyridine with sulfuric acid (H2SO4) to generate methyl 4-chloro-2-aminopyridine -2-carboxylate;
4. Hydrolysis of methyl 4-chloro-2-aminopyridine-2-carboxylate using hydrochloric acid (HCl) to give Methyl 4-aminopyridine-2-carboxylate.

Safety Information:
- Methyl 4-aminopyridine-2-carboxylate is stable at room temperature, but flammable at high temperature or open flame;
-The potential hazards to the human body are not fully understood, so you need to wear protective gloves and goggles during operation;
-Inhalation of the dust of this compound may cause irritation, so it is necessary to ensure operation in a well-ventilated environment;
-Local regulations and rules need to be followed during storage and disposal.

Last Update：2024-04-10 22:29:15