pyridine, 2-methoxy-6-(trifluoromethyl)-

pyridine, 2-methoxy-6-(trifluoromethyl)- - Names and Identifiers

Name	2-Methoxy-6-(trifluoromethyl)pyridine
Synonyms	189467 2-Methoxy-6-(trifluoromethyl)pyridine pyridine, 2-methoxy-6-(trifluoromethyl)-
CAS	34486-18-5

pyridine, 2-methoxy-6-(trifluoromethyl)- - Physico-chemical Properties

Molecular Formula	C7H6F3NO
Molar Mass	177.124
Density	1.263±0.06 g/cm3(Predicted)
Boling Point	149.8±40.0 °C(Predicted)
pKa	-1.28±0.12(Predicted)
Storage Condition	2-8°C

pyridine, 2-methoxy-6-(trifluoromethyl)- - Upstream Downstream Industry

Downstream Products

(2-Methoxy-6-(trifluoroMethyl)pyridin-3-yl)boronic acid

pyridine, 2-methoxy-6-(trifluoromethyl)- - Introduction

2-Methoxy-6-(trifluoromethyl)pyridine is an organic compound with the chemical formula C7H6F3NO. It is a colorless liquid with a special smell. The following is a detailed description of its nature, use, formulation and safety information:

Nature:
-Appearance: colorless liquid
-Molecular weight: 189.12g/mol
-Boiling point: 100-101 ℃
-Density: 1.34g/cm³
-refractive index: 1.420-1.423
-Solubility: can be dissolved in organic solvents such as ethanol and dichloromethane

Use:
- 2-Methoxy-6-(trifluoromethyl)pyridine is a multifunctional compound, which is widely used in organic synthesis, pharmaceutical chemistry and pesticides.
-It can be used as a catalyst and reaction intermediate, participating in a variety of reactions, such as nitration, fluorination and refining processes.
-In medicinal chemistry, it can be used to synthesize potential anti-tumor drugs and other biologically active molecules.
-In the field of pesticides, it can be used as a component of pesticides and fungicides.

Method:
The preparation of 2-Methoxy-6-(trifluoromethyl)pyridine generally uses the following steps:
1. Condensation reaction of 2-methoxypyridine with trifluoroformic acid to generate the corresponding Ketal compound.
2. The Ketal compound is reacted with hydrofluoric acid to undergo a deketalization reaction to obtain 2-Methoxy-6-(trifluoromethyl)pyridine.

Safety Information:
- 2-Methoxy-6-(trifluoromethyl)pyridine is an organic compound and should be handled with caution. Follow safe operating procedures and wear personal protective equipment, such as gloves and protective glasses.
-It is a flammable liquid and should be kept away from fire and high temperature environment. Store in a cool, dry place away from direct sunlight.
-During operation, care should be taken to avoid inhalation, skin contact and ingestion. In the case of accidental contact, rinse immediately with plenty of water and seek medical help.
-Detailed safety information can be found in the safety data sheet (MSDS) provided by the relevant chemical provider.

Last Update：2024-04-09 15:18:02