pyrimidine-2-carboxylic acid
pyrimidine-2-carboxylic acid
CAS: 31519-62-7
Molecular Formula: C5H4N2O2
pyrimidine-2-carboxylic acid - Names and Identifiers
| Name | pyrimidine-2-carboxylic acid |
| Synonyms | RARECHEM AL BO 0759 TIMTEC-BB SBB005602 2-CARBOXY-PYRIMIDINE 2-PYRIMIDINECARBOXYLIC ACID PYRIMIDINE-2-CARBOXYLIC ACID pyrimidine-2-carboxylic acid 2-Pyrimidinecarboxylic acid (6CI,8CI,9CI) 2-Pyrimidinecarboxylic acid(Crystalline solid) |
| CAS | 31519-62-7 |
| InChI | InChI=1/C5H4N2O2/c8-5(9)4-6-2-1-3-7-4/h1-3H,(H,8,9) |
| InChIKey | ZFCHNZDUMIOWFV-UHFFFAOYSA-N |
pyrimidine-2-carboxylic acid - Physico-chemical Properties
| Molecular Formula | C5H4N2O2 |
| Molar Mass | 124.1 |
| Density | 1.403±0.06 g/cm3(Predicted) |
| Melting Point | 182-185°C |
| Boling Point | 362.6±25.0 °C(Predicted) |
| Flash Point | 173.109°C |
| Solubility | Soluble in ethanol (~1 mg/ml), DMSO (30 mg/ml), DMF (30 mg/ml), and solution of PBS(pH |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | White to white-like solid |
| Color | White to Almost white |
| Maximum wavelength(λmax) | ['246nm(H2O (pH 7))(lit.)'] |
| pKa | 3.08±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.579 |
| MDL | MFCD00856161 |
| Use | A synthetic intermediate |
pyrimidine-2-carboxylic acid - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| HS Code | 29335990 |
| Hazard Class | IRRITANT |
pyrimidine-2-carboxylic acid - Introduction
pyrimidine-2-carboxylic acid is an organic compound with the chemical formula cwww.tianyancha.com H, n₂ O.
Nature:
-Appearance: pyrimidine-2-carboxylic acid is white crystal or crystalline powder.
-Melting point: About 180-185°C.
-Solubility: pyrimidine-2-carboxylic acid has low solubility in water, and its solubility is better in other polar solvents.
Use:
-Chemical synthesis: pyrimidine-2-carboxylic acid is an important intermediate for the synthesis of other organic compounds, and is often used to prepare more complex pyrimidine derivatives.
-Drugs: pyrimidine-2-carboxylic acid has the potential to be used as a precursor for antiviral, antineoplastic and antibacterial drugs.
Method:
pyrimidine-2-carboxylic acid can be prepared by the following steps:
1.2-pyrimidine reacts with chloroacetic acid to generate pyrimidine-2-carboxylic acid chloromethyl ester.
2. pyrimidine-2-carboxylic acid chloromethyl Ester reacts with water to generate pyrimidine-2-carboxylic acid.
Safety Information:
pyrimidine-2-carboxylic acid is generally a relatively safe compound under normal conditions of use. But as a chemical, it can still present a number of safety risks, including:
-Irritating to skin and eyes, so care should be taken to avoid contact with eyes and skin during use.
-During operation, care should be taken to avoid inhaling dust or solution gas.
-Should be properly stored, away from fire and oxidizing agents.
-Follow proper laboratory safety procedures for use and disposal. It is best to check the safety data sheet of the chemical before use to obtain more detailed and accurate safety information.
Nature:
-Appearance: pyrimidine-2-carboxylic acid is white crystal or crystalline powder.
-Melting point: About 180-185°C.
-Solubility: pyrimidine-2-carboxylic acid has low solubility in water, and its solubility is better in other polar solvents.
Use:
-Chemical synthesis: pyrimidine-2-carboxylic acid is an important intermediate for the synthesis of other organic compounds, and is often used to prepare more complex pyrimidine derivatives.
-Drugs: pyrimidine-2-carboxylic acid has the potential to be used as a precursor for antiviral, antineoplastic and antibacterial drugs.
Method:
pyrimidine-2-carboxylic acid can be prepared by the following steps:
1.2-pyrimidine reacts with chloroacetic acid to generate pyrimidine-2-carboxylic acid chloromethyl ester.
2. pyrimidine-2-carboxylic acid chloromethyl Ester reacts with water to generate pyrimidine-2-carboxylic acid.
Safety Information:
pyrimidine-2-carboxylic acid is generally a relatively safe compound under normal conditions of use. But as a chemical, it can still present a number of safety risks, including:
-Irritating to skin and eyes, so care should be taken to avoid contact with eyes and skin during use.
-During operation, care should be taken to avoid inhaling dust or solution gas.
-Should be properly stored, away from fire and oxidizing agents.
-Follow proper laboratory safety procedures for use and disposal. It is best to check the safety data sheet of the chemical before use to obtain more detailed and accurate safety information.
Last Update：2024-04-09 21:32:40
Supplier List
Spot supply
Product Name: pyrimidine-2-carboxylic acid Request for quotationCAS: 31519-62-7
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Product Name: pyrimidine-2-carboxylic acid Request for quotation
CAS: 31519-62-7
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 31519-62-7
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Spot supply
Product Name: Avanafil Impurity 115 Visit Supplier Webpage Request for quotationCAS: 31519-62-7
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: Pyrimidine-2-carboxylic acid Visit Supplier Webpage Request for quotation
CAS: 31519-62-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 31519-62-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: pyrimidine-2-carboxylic acid Request for quotationCAS: 31519-62-7
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Product Name: pyrimidine-2-carboxylic acid Request for quotation
CAS: 31519-62-7
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 31519-62-7
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Spot supply
Product Name: Avanafil Impurity 115 Visit Supplier Webpage Request for quotationCAS: 31519-62-7
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: Pyrimidine-2-carboxylic acid Visit Supplier Webpage Request for quotation
CAS: 31519-62-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 31519-62-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History