quinoline, 2-chloro-3-iodo-
2-chloro-3-iodoquinoline
CAS: 128676-85-7
Molecular Formula: C9H5ClIN
quinoline, 2-chloro-3-iodo- - Names and Identifiers
| Name | 2-chloro-3-iodoquinoline |
| Synonyms | -CHLORO-3-IODOQUINOLINE 2-chloro-3-iodoquinoline 2-CHLORO-3-IODOQUINOLINE quinoline, 2-chloro-3-iodo- |
| CAS | 128676-85-7 |
| InChI | InChI=1/C9H5ClIN/c10-9-7(11)5-6-3-1-2-4-8(6)12-9/h1-5H |
quinoline, 2-chloro-3-iodo- - Physico-chemical Properties
| Molecular Formula | C9H5ClIN |
| Molar Mass | 289.5 |
| Density | 1.92g/cm3 |
| Boling Point | 351.582°C at 760 mmHg |
| Flash Point | 166.431°C |
| Vapor Presure | 0mmHg at 25°C |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.727 |
quinoline, 2-chloro-3-iodo- - Introduction
2-Chloro-3-iodoquinoline is an organic compound with the chemical formula C9H5ClIN. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2-Chloro-3-iodoquinoline is a white to pale yellow solid.
-Melting point: about 180-182°C.
-Boiling point: about 355-360 ℃.
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol, acetone, etc.
Use:
-2-Chloro-3-iodoquinoline is often used as an important intermediate in organic synthesis.
-It can be used in the synthesis of pesticides, pharmaceuticals, dyes and other organic compounds.
Preparation Method:
The preparation of 2-chloro-3-iodoquinoline can be carried out by the following steps:
1.2-chloroquinoline is reacted with sodium iodide under alkaline conditions.
2. The reaction is carried out in an appropriate solvent, and solvents such as alcohols, ketones, and esters can be used.
3. The crude product was obtained by filtration, and then purified by crystallization or column chromatography.
Safety Information:
For the safe handling of 2-chloro-3-iodoquinoline, the following precautions should be observed:
-Wear protective gloves, goggles and masks during operation.
-Avoid inhaling its dust, gas or fumes, and avoid contact with eyes, skin and respiratory system.
-Keep sealed during storage and avoid contact with flammable or corrosive substances such as oxidants and acids.
-Operate under safe ventilation conditions to avoid ignition.
-In case of accidental contact or inhalation, seek medical attention immediately and bring information about the compound.
Nature:
-Appearance: 2-Chloro-3-iodoquinoline is a white to pale yellow solid.
-Melting point: about 180-182°C.
-Boiling point: about 355-360 ℃.
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol, acetone, etc.
Use:
-2-Chloro-3-iodoquinoline is often used as an important intermediate in organic synthesis.
-It can be used in the synthesis of pesticides, pharmaceuticals, dyes and other organic compounds.
Preparation Method:
The preparation of 2-chloro-3-iodoquinoline can be carried out by the following steps:
1.2-chloroquinoline is reacted with sodium iodide under alkaline conditions.
2. The reaction is carried out in an appropriate solvent, and solvents such as alcohols, ketones, and esters can be used.
3. The crude product was obtained by filtration, and then purified by crystallization or column chromatography.
Safety Information:
For the safe handling of 2-chloro-3-iodoquinoline, the following precautions should be observed:
-Wear protective gloves, goggles and masks during operation.
-Avoid inhaling its dust, gas or fumes, and avoid contact with eyes, skin and respiratory system.
-Keep sealed during storage and avoid contact with flammable or corrosive substances such as oxidants and acids.
-Operate under safe ventilation conditions to avoid ignition.
-In case of accidental contact or inhalation, seek medical attention immediately and bring information about the compound.
Last Update：2024-04-09 02:00:41
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CAS: 128676-85-7
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Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 128676-85-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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