tert-Butyl 3-(hydrazinecarbonyl)-azetidine-1-carboxylate
tert-Butyl 3-(hydrazinecarbonyl)-azetidine-1-carboxylate
CAS: 1001907-44-3
Molecular Formula: C9H17N3O3
tert-Butyl 3-(hydrazinecarbonyl)-azetidine-1-carboxylate - Names and Identifiers
tert-Butyl 3-(hydrazinecarbonyl)-azetidine-1-carboxylate - Physico-chemical Properties
| Molecular Formula | C9H17N3O3 |
| Molar Mass | 215.25 |
| Storage Condition | 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD16556176 |
tert-Butyl 3-(hydrazinecarbonyl)-azetidine-1-carboxylate - Introduction
tert-Butyl 3-(hydrazinecarbonyl)-azetidine-1-carboxylate is an organic compound with the chemical formula C9H16N4O3.
Nature:
-Appearance is colorless liquid or solid;
-Molecular weight of 228.25g/mol;
-Has low solubility, soluble in acidic and neutral organic solvents, such as dimethyl sulfoxide, chloroform and acetonitrile;
-It has good thermal stability at high temperature.
Use:
tert-Butyl 3-(hydrazinecarbonyl)-azetidine-1-carboxylate can be used as an intermediate in organic synthesis and is widely used in the fields of medicine, pesticide and material science. It is often used in the synthesis of other organic compounds, such as for the research and development of specific drugs or active substances.
Preparation Method:
The preparation of tert-Butyl 3-(hydrazinecarbonyl)-azetidine-1-carboxylate can usually be achieved by the following steps:
1.1-bromo -3-tert-butyl isonitrile reacts with hydrazine to generate 3-bromo -1-tert-butyl -2-guanidine.
2.3-bromo -1-tert-butyl -2-guanidine is reacted with the bromo derivative of dimethylcarbamide to generate 3-(hydrazinecarbonyl) azabutane -1-amine.
3. Finally, 3-(hydrazinecarbonyl) azetan-1-amine is reacted with tert-butyl chloroformate to form the tert-Butyl 3-(hydrazinecarbonyl)-azetidine-1-carboxylate.
Safety Information:
Limited safety information regarding tert-Butyl 3-(hydrazinecarbonyl)-azetidine-1-carboxylate. As users of chemicals, they should follow appropriate laboratory safety practices, including wearing personal protective equipment (such as gloves, glasses, and laboratory coats), and avoid contact with skin and eyes. In addition, it should be used in a well-ventilated environment, and proper storage and handling methods should be followed to avoid fire, explosion and other dangerous events. If necessary, it is recommended to consult the Material Safety Data Sheet (MSDS) or consult a relevant professional for detailed safety information.
Nature:
-Appearance is colorless liquid or solid;
-Molecular weight of 228.25g/mol;
-Has low solubility, soluble in acidic and neutral organic solvents, such as dimethyl sulfoxide, chloroform and acetonitrile;
-It has good thermal stability at high temperature.
Use:
tert-Butyl 3-(hydrazinecarbonyl)-azetidine-1-carboxylate can be used as an intermediate in organic synthesis and is widely used in the fields of medicine, pesticide and material science. It is often used in the synthesis of other organic compounds, such as for the research and development of specific drugs or active substances.
Preparation Method:
The preparation of tert-Butyl 3-(hydrazinecarbonyl)-azetidine-1-carboxylate can usually be achieved by the following steps:
1.1-bromo -3-tert-butyl isonitrile reacts with hydrazine to generate 3-bromo -1-tert-butyl -2-guanidine.
2.3-bromo -1-tert-butyl -2-guanidine is reacted with the bromo derivative of dimethylcarbamide to generate 3-(hydrazinecarbonyl) azabutane -1-amine.
3. Finally, 3-(hydrazinecarbonyl) azetan-1-amine is reacted with tert-butyl chloroformate to form the tert-Butyl 3-(hydrazinecarbonyl)-azetidine-1-carboxylate.
Safety Information:
Limited safety information regarding tert-Butyl 3-(hydrazinecarbonyl)-azetidine-1-carboxylate. As users of chemicals, they should follow appropriate laboratory safety practices, including wearing personal protective equipment (such as gloves, glasses, and laboratory coats), and avoid contact with skin and eyes. In addition, it should be used in a well-ventilated environment, and proper storage and handling methods should be followed to avoid fire, explosion and other dangerous events. If necessary, it is recommended to consult the Material Safety Data Sheet (MSDS) or consult a relevant professional for detailed safety information.
Last Update：2024-04-09 21:54:55
