tert-Butyl 3-(iodomethyl)pyrrolidine-1-carboxylate

tert-Butyl 3-(iodomethyl)pyrrolidine-1-carboxylate - Names and Identifiers

Name	tert-Butyl 3-(iodomethyl)pyrrolidine-1-carboxylate
Synonyms	Boc-3-Iodomethyl-pyrrolidine N-Boc-3-iodomethyl-pyrrolidine 1-Boc-3-(IodoMethyl)pyrrolidine 1-Boc-3-(iodomethyl)-pyrrolidine TERT-BUTYL 3-(IODOMETHYL)PYRROLIDINE-1-CARBOXYLATE tert-butyl 3-(iodomethyl)-1-pyrrolidinecarboxylate tert-Butyl 3-(iodomethyl)pyrrolidine-1-carboxylate 3-Iodomethylpyrrolidine-1-carboxylic acid tert-butyl ester 3-IODOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 1-Pyrrolidinecarboxylic acid, 3-(iodomethyl)-, 1,1-dimethylethyl ester
CAS	479622-36-1
InChI	InChI=1/C10H18INO2/c1-10(2,3)14-9(13)12-5-4-8(6-11)7-12/h8H,4-7H2,1-3H3

tert-Butyl 3-(iodomethyl)pyrrolidine-1-carboxylate - Physico-chemical Properties

Molecular Formula	C10H18INO2
Molar Mass	311.16
Density	1.504
Boling Point	319.0±15.0 °C(Predicted)
Flash Point	146.7°C
Vapor Presure	0.000348mmHg at 25°C
pKa	-2.01±0.40(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.535

tert-Butyl 3-(iodomethyl)pyrrolidine-1-carboxylate - Risk and Safety

Risk Codes	36 - Irritating to the eyes
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany	3
Hazard Class	IRRITANT

tert-Butyl 3-(iodomethyl)pyrrolidine-1-carboxylate - Introduction

tert-Butyl 3-(iodomethyl)pyrrolidine-1-carboxylate is an organic compound with the chemical formula C10H17INO2.

Nature:
-Appearance: colorless or light yellow oily liquid
-Solubility: Soluble in organic solvents, such as ethanol, dichloromethane
-Melting point: approximately -20°C
-Boiling point: about 224-225°C
-Density: approx. 1.41g/cm³

Use:
tert-Butyl 3-(iodomethyl)pyrrolidine-1-carboxylate is commonly used as an intermediate in organic synthesis and can be used to synthesize a variety of biologically active compounds. It can be used as a raw material for the synthesis of certain drugs, fragrances and other organic compounds.

Preparation Method:
A commonly used synthesis method is to react tert-butyl pyrrolidine-l-carboxylate with methyl iodide under the catalysis of a base to generate tert-Butyl 3-(iodomethyl)pyrrolidine-1-carboxylate.

Safety Information:
Because tert-Butyl 3-(iodomethyl)pyrrolidine-1-carboxylate is an organic compound, the following safety precautions should be paid attention to when using:
-Avoid inhalation of vapors and contact with skin, and take appropriate protective measures, such as wearing protective gloves and masks.
-Good ventilation conditions should be maintained during use.
-Avoid contact with strong oxidants and strong acids to prevent dangerous reactions.
-Storage should be sealed and kept away from fire and high temperature.

When handling and using tert-Butyl 3-(iodomethyl)pyrrolidine-1-carboxylate, carefully read and follow relevant safety instructions according to the actual situation.

Last Update：2024-04-09 19:05:49