tert-Butyl 7-hydroxy-2,3-dihydro-1H-indole-1-carboxylate
1H-Indole-1-carboxylic acid, 2,3-dihydro-7-hydroxy-, 1,1-dimethylethyl ester
CAS: 945771-04-0
Molecular Formula: C13H17NO3
tert-Butyl 7-hydroxy-2,3-dihydro-1H-indole-1-carboxylate - Names and Identifiers
tert-Butyl 7-hydroxy-2,3-dihydro-1H-indole-1-carboxylate - Physico-chemical Properties
| Molecular Formula | C13H17NO3 |
| Molar Mass | 235.28 |
| Density | 1.205±0.06 g/cm3(Predicted) |
| Boling Point | 345.3±41.0 °C(Predicted) |
| pKa | 9.88±0.20(Predicted) |
| Storage Condition | 2-8°C |
tert-Butyl 7-hydroxy-2,3-dihydro-1H-indole-1-carboxylate - Introduction
1H-Indole-1-carboxylic acid, 2,3-dihydro-7-hydroxy-, 1,1-dimethylethyl ester is an organic compound with the chemical formula C16H19NO3. It is a white solid, soluble in organic solvents such as dimethyl sulfoxide and methylene chloride.
This compound is commonly used in the synthesis of catalytic reactions and intermediates in organic synthesis. It can be used as a substrate for indoline and hydroxylating reagents for the synthesis of biologically active compounds such as drug molecules and natural products.
the method for preparing 1H-indole-1-carboxylic acid, 2,3-dihydroxy-7-hydroxyester-, 1,1-dimethylethyl ester is to react N-Boc-indoline with hydrogen peroxide in the presence of acetic acid, and then to obtain the target product through deprotection under acid catalytic conditions.
From a safety point of view, it is important to note that this compound is irritating and should avoid contact with skin and eyes. Good laboratory safety measures should be taken during operation, such as wearing protective gloves and goggles, and ensuring that the operation is carried out in a well-ventilated place. In addition, avoid exposing it to high temperatures and fire sources to avoid harmful gases. During handling and storage, it should be properly managed to avoid any accidents.
This compound is commonly used in the synthesis of catalytic reactions and intermediates in organic synthesis. It can be used as a substrate for indoline and hydroxylating reagents for the synthesis of biologically active compounds such as drug molecules and natural products.
the method for preparing 1H-indole-1-carboxylic acid, 2,3-dihydroxy-7-hydroxyester-, 1,1-dimethylethyl ester is to react N-Boc-indoline with hydrogen peroxide in the presence of acetic acid, and then to obtain the target product through deprotection under acid catalytic conditions.
From a safety point of view, it is important to note that this compound is irritating and should avoid contact with skin and eyes. Good laboratory safety measures should be taken during operation, such as wearing protective gloves and goggles, and ensuring that the operation is carried out in a well-ventilated place. In addition, avoid exposing it to high temperatures and fire sources to avoid harmful gases. During handling and storage, it should be properly managed to avoid any accidents.
Last Update：2024-04-09 19:05:53
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Product Name: 1H-INDOLE-1-CARBOXYLIC ACID,2,3-DIHYDRO-7-HYDROXY-,1,1-DIMETHYLETHYL ESTER Visit Supplier Webpage Request for quotation
CAS: 945771-04-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 945771-04-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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