tert-Butyl trans-4-(hydroxymethyl)cyclohexylcarbamate FP160825
tert-Butyl [trans-4-(hydroxymethyl)cyclohexyl]carbamate
CAS: 239074-29-4
Molecular Formula: C12H23NO3
tert-Butyl trans-4-(hydroxymethyl)cyclohexylcarbamate FP160825 - Names and Identifiers
tert-Butyl trans-4-(hydroxymethyl)cyclohexylcarbamate FP160825 - Physico-chemical Properties
| Molecular Formula | C12H23NO3 |
| Molar Mass | 229.32 |
| Density | 1.05±0.1 g/cm3(Predicted) |
| Boling Point | 351.6±11.0 °C(Predicted) |
| Flash Point | 166.444°C |
| Solubility | Slightly Soluble (4.4 g/L) (25°C). |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Solid |
| pKa | 12.50±0.40(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.485 |
tert-Butyl trans-4-(hydroxymethyl)cyclohexylcarbamate FP160825 - Introduction
tert-Butyl [trans-4-(hydroxymethyl)cyclohexyl]carbamate is an organic compound with the chemical formula C14H27NO3. The following is a description of its nature, use, preparation and safety information:
Nature:
tert-Butyl [trans-4-(hydroxymethyl)cyclohexyl]carbamate is a colorless, transparent liquid. It is soluble in many organic solvents, such as ethanol, ethers and ketones. It has a density of 0.998g/cm³, a boiling point of 228-229 ° C, and a melting point of <-20 ° C. It is a stable compound that can be stored at room temperature.
Use:
tert-Butyl [trans-4-(hydroxymethyl)cyclohexyl]carbamate is often used as a protecting group in organic synthesis. It can be reacted with an amine to form the corresponding amine salt, followed by selective removal of the Amine protecting group after the synthesis is complete. It can also be used as an ester protecting group in the esterification reaction to protect the hydroxyl groups of alcohol compounds to prevent them from accidentally reacting in the reaction.
Method:
The method for preparing tert-Butyl [trans-4-(hydroxymethyl)cyclohexyl]carbamate is usually to react cyclohexane amine with tert-butyl pyruvate under alkaline conditions. First, cyclohexane amine is reacted with sodium carbonate or sodium hydroxide to form a cyclohexane amine salt. Then, tert-butyl pyruvate was added to the reaction mixture and heated to react. Finally, the target product is obtained by acidification and crystallization.
Safety Information:
tert-Butyl [trans-4-(hydroxymethyl)cyclohexyl]carbamate is an organic compound and has certain safety risks. May cause irritation to the eyes and skin when contacted and may cause respiratory irritation. Appropriate protective equipment such as gloves and eye protection should be worn during use. If exposed or ingested, wash the affected area immediately or seek medical help.
These are just the basic introduction of tert-Butyl [trans-4-(hydroxymethyl)cyclohexyl]carbamate. The specific use should follow the laboratory's safe operation procedures and operate in accordance with relevant laws and regulations.
Nature:
tert-Butyl [trans-4-(hydroxymethyl)cyclohexyl]carbamate is a colorless, transparent liquid. It is soluble in many organic solvents, such as ethanol, ethers and ketones. It has a density of 0.998g/cm³, a boiling point of 228-229 ° C, and a melting point of <-20 ° C. It is a stable compound that can be stored at room temperature.
Use:
tert-Butyl [trans-4-(hydroxymethyl)cyclohexyl]carbamate is often used as a protecting group in organic synthesis. It can be reacted with an amine to form the corresponding amine salt, followed by selective removal of the Amine protecting group after the synthesis is complete. It can also be used as an ester protecting group in the esterification reaction to protect the hydroxyl groups of alcohol compounds to prevent them from accidentally reacting in the reaction.
Method:
The method for preparing tert-Butyl [trans-4-(hydroxymethyl)cyclohexyl]carbamate is usually to react cyclohexane amine with tert-butyl pyruvate under alkaline conditions. First, cyclohexane amine is reacted with sodium carbonate or sodium hydroxide to form a cyclohexane amine salt. Then, tert-butyl pyruvate was added to the reaction mixture and heated to react. Finally, the target product is obtained by acidification and crystallization.
Safety Information:
tert-Butyl [trans-4-(hydroxymethyl)cyclohexyl]carbamate is an organic compound and has certain safety risks. May cause irritation to the eyes and skin when contacted and may cause respiratory irritation. Appropriate protective equipment such as gloves and eye protection should be worn during use. If exposed or ingested, wash the affected area immediately or seek medical help.
These are just the basic introduction of tert-Butyl [trans-4-(hydroxymethyl)cyclohexyl]carbamate. The specific use should follow the laboratory's safe operation procedures and operate in accordance with relevant laws and regulations.
Last Update：2024-04-10 22:29:15
Supplier List
Product Name: Tert-Butyl Trans-(4-Hydroxymethyl)Cyclohexylcarbamate Visit Supplier Webpage Request for quotation
CAS: 239074-29-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 239074-29-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: Tert-Butyl Trans-(4-Hydroxymethyl)Cyclohexylcarbamate Visit Supplier Webpage Request for quotation
CAS: 239074-29-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 239074-29-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History