tert-butyl (2R)-2-(2-hydroxyethyl)piperidine-1-carboxylate - Names and Identifiers
Name | tert-butyl (2R)-2-(2-hydroxyethyl)piperidine-1-carboxylate
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Synonyms | (R)-1-N-BOC-PIPERIDINE-2-ETHANOL (R)-1-N-Boc-piperidine-2-ethanol (R)-tert-Butyl2-(2-hydroxyethyl)piperidine-1-carboxylate tert-Butyl (2R)-2-(2-hydroxyethyl)piperidine-1-carboxylate tert-butyl (2R)-2-(2-hydroxyethyl)piperidine-1-carboxylate 1-Piperidinecarboxylic acid, 2-(2-hydroxyethyl)-, 1,1-dimethylethyl ester, (2R)- 1-Piperidinecarboxylic acid, 2-(2-hydroxyethyl)-, 1,1-dimethylethyl ester, (2R)-
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CAS | 250249-85-5
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InChI | InChI=1/C12H23NO3/c1-12(2,3)16-11(15)13-8-5-4-6-10(13)7-9-14/h10,14H,4-9H2,1-3H3/t10-/m1/s1 |
tert-butyl (2R)-2-(2-hydroxyethyl)piperidine-1-carboxylate - Physico-chemical Properties
Molecular Formula | C12H23NO3
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Molar Mass | 229.32 |
Density | 1.043 |
Boling Point | 324.1±15.0 °C(Predicted) |
Flash Point | 149.8°C |
Vapor Presure | 1.97E-05mmHg at 25°C |
pKa | 15.15±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.478 |
tert-butyl (2R)-2-(2-hydroxyethyl)piperidine-1-carboxylate - Introduction
tert-butyl (2R)-2-(2-hydroxyethyl)piperidine-1-carboxylate, also known as tert-butyl (2R)-2-(2-hydroxyethyl)piperidine-1-carboxylate, is an organic compound. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: Usually white crystals or solid powder.
-molecular formula: C14H25NO3.
-Molecular weight: 259.35g/mol.
-Melting point: About 60-65 degrees Celsius.
-Solubility: Soluble in common organic solvents such as ethanol, chloroform and dichloromethane.
Use:
- tert-butyl (2R)-2-(2-hydroxyethyl)piperidine-1-carboxylate as a chiral intermediate, commonly used in organic synthesis reactions.
-It can be used as an important raw material for the synthesis of drugs, pesticides, cosmetics and other organic compounds.
Method:
-A common preparation method is obtained by reacting N-Boc-piperidine with 2-chloroethanol. tert-butyl (2R)-2-(2-hydroxyethyl)piperidine-1-carboxylate.
Safety Information:
- tert-butyl (2R)-2-(2-hydroxyethyl)piperidine-1-carboxylate are generally relatively safe under correct operation. However, it is still an organic compound, and the following points should be noted:
-It may be irritating to the eyes, skin and respiratory tract and direct contact should be avoided.
-Use with appropriate protective equipment, such as laboratory gloves and goggles.
-Avoid ignition and contact with strong oxidants during handling and storage.
Last Update:2024-04-09 20:45:29