tert-butyl (4-bromo-2-fluorophenyl)carbamate

tert-butyl (4-bromo-2-fluorophenyl)carbamate - Names and Identifiers

Name	N-Boc-4-Bromo-2-fluoroaniline
Synonyms	N-Boc-4-Bromo-2-fluoroaniline tert-butyl-4-bromo-2-flurophenylcarbamate tert-butyl (4-bromo-2-fluorophenyl)carbamate tert-Butyl N-(4-bromo-2-fluorophenyl)carbamate (4-Bromo-2-fluorophenyl)carbamic acid tert-butyl ester Carbamic acid, N-(4-bromo-2-fluorophenyl)-, 1,1-dimethylethyl ester
CAS	209958-42-9
InChI	InChI=1/C11H13BrFNO2/c1-11(2,3)16-10(15)14-9-5-4-7(12)6-8(9)13/h4-6H,1-3H3,(H,14,15)

tert-butyl (4-bromo-2-fluorophenyl)carbamate - Physico-chemical Properties

Molecular Formula	C11H13BrFNO2
Molar Mass	290.13
Density	1.459±0.06 g/cm3(Predicted)
Boling Point	272.2±30.0 °C(Predicted)
Flash Point	118.446°C
Vapor Presure	0.006mmHg at 25°C
pKa	11.90±0.70(Predicted)
Storage Condition	2-8°C
Refractive Index	1.555

tert-butyl (4-bromo-2-fluorophenyl)carbamate - Introduction

The chemical properties of a N-Boc-4-Bromo-2-fluoroaniline mainly depend on its molecular structure. It is an organic compound with the molecular formula C14H16BrFN, which has a N-Boc protecting Group, a bromine atom and a fluorine atom attached to the benzene ring. The following is a detailed description of its nature, use, preparation and safety information:

Nature:
-Appearance: N-Boc-4-Bromo-2-fluoroaniline is a white crystal or crystalline powder.
-Melting point: Its melting point range is usually 67-71 degrees Celsius.
-Solubility: It has high solubility in common organic solvents such as dichloromethane, ether and benzene.

Use:
- N-Boc-4-Bromo-2-fluoroaniline is an important organic synthesis intermediate, which has a wide range of applications in the field of drug synthesis and material science.
-It is commonly used in the synthesis of new drug molecules, functional materials and pesticides.

Method:
-Generally, the preparation of N-Boc-4-Bromo-2-fluoroaniline is obtained by reacting 4-bromo-2-fluoroaniline with a N-Boc protecting reagent. The reaction conditions may be carried out in an organic solvent with addition of a catalyst and temperature control.

Safety Information:
- N-Boc-4-Bromo-2-fluoroaniline is a chemical and care should be taken to comply with the relevant safety procedures.
-It may irritate the eyes, skin and respiratory tract, so avoid direct contact when using it.
-When storing, it should be stored in a dry, cool place, away from fire and high temperature.
-Wear suitable protective equipment such as chemical protective gloves, goggles and protective clothing when handling the compound. If exposed or inhaled, seek medical attention immediately.

Last Update：2024-04-09 20:49:11