tert-butyl 2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonate
T-butyl-(3R,5S)-6-hydroxy 3,5-O-isopropylidene 3,5-dihydroxyhexanoate
CAS: 124655-09-0
Molecular Formula: C13H24O5
tert-butyl 2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonate - Names and Identifiers
tert-butyl 2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonate - Physico-chemical Properties
| Molecular Formula | C13H24O5 |
| Molar Mass | 260.33 |
| Density | 1.030 |
| Boling Point | 331°C |
| Flash Point | 113°C |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Oil |
| Color | Pale Yellow to Brown to Thick |
| pKa | 14.25±0.10(Predicted) |
| Storage Condition | Inert atmosphere,2-8°C |
| Refractive Index | 1.4500-1.4540 |
tert-butyl 2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonate - Risk and Safety
| HS Code | 29329990 |
tert-butyl 2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonate - Introduction
(4R-Cis)-tert-butyl 6-hydroxymethyl-2,2-dimethyl-1, 3-dioxane-4-acetate, often abbreviated as Tertbutyl 6-hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-carboxylate.
Nature:
-Appearance: colorless liquid
-Molecular formula: C14H26O5
-Solubility: Soluble in common organic solvents such as ethers, alcohols and esters
-Melting Point/Boiling Point: No Report
-Relative density: no report
-Stability: stable, avoid contact with strong oxidants and high temperatures
Use:
- (4R-Cis)-6-hydroxymethyl-2, 2-dimethyl-1, 3-dioxane-4-acetic acid tert-butyl ester is commonly used as a chiral intermediate for the synthesis of a variety of compounds and drugs.
-It can be used as a protecting group in organic synthesis to provide protection for hydroxyl groups.
-It can also be used for asymmetric catalytic reactions in drug synthesis and synthesis of chiral drugs.
Preparation Method:
The specific preparation method can integrate multi-step reactions. One common preparation is by reacting 1,4-cyclohexanediol with tert-butyryl chloride to give a tert-butyrate compound, which is then converted to (4R-Cis)-6-hydroxymethyl-2, 2-dimethyl-1, 3-dioxane-4-acetic acid tert-butyl ester by photochemical hydroxymethylation.
Safety Information:
- (4R-Cis)-6-hydroxymethyl-2, 2-dimethyl-1, 3-dioxane-4-acetic acid tert-butyl ester specific safety information may vary from manufacturer to supplier, please refer to the relevant safety technical instructions and instructions when using.
-Wear appropriate personal protective equipment such as chemical goggles, protective gloves and protective clothing when used.
-Avoid contact with skin, eyes and respiratory tract. In case of contact or aspiration, rinse immediately with water and seek medical advice.
-During use and storage, please follow the correct operation and storage requirements of chemicals, avoid mixed storage with other chemicals, and keep away from fire and heat sources.
Nature:
-Appearance: colorless liquid
-Molecular formula: C14H26O5
-Solubility: Soluble in common organic solvents such as ethers, alcohols and esters
-Melting Point/Boiling Point: No Report
-Relative density: no report
-Stability: stable, avoid contact with strong oxidants and high temperatures
Use:
- (4R-Cis)-6-hydroxymethyl-2, 2-dimethyl-1, 3-dioxane-4-acetic acid tert-butyl ester is commonly used as a chiral intermediate for the synthesis of a variety of compounds and drugs.
-It can be used as a protecting group in organic synthesis to provide protection for hydroxyl groups.
-It can also be used for asymmetric catalytic reactions in drug synthesis and synthesis of chiral drugs.
Preparation Method:
The specific preparation method can integrate multi-step reactions. One common preparation is by reacting 1,4-cyclohexanediol with tert-butyryl chloride to give a tert-butyrate compound, which is then converted to (4R-Cis)-6-hydroxymethyl-2, 2-dimethyl-1, 3-dioxane-4-acetic acid tert-butyl ester by photochemical hydroxymethylation.
Safety Information:
- (4R-Cis)-6-hydroxymethyl-2, 2-dimethyl-1, 3-dioxane-4-acetic acid tert-butyl ester specific safety information may vary from manufacturer to supplier, please refer to the relevant safety technical instructions and instructions when using.
-Wear appropriate personal protective equipment such as chemical goggles, protective gloves and protective clothing when used.
-Avoid contact with skin, eyes and respiratory tract. In case of contact or aspiration, rinse immediately with water and seek medical advice.
-During use and storage, please follow the correct operation and storage requirements of chemicals, avoid mixed storage with other chemicals, and keep away from fire and heat sources.
Last Update：2024-04-09 19:05:46
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Spot supply
Product Name: Rosuvastatin Impurity 70 Visit Supplier Webpage Request for quotationCAS: 124655-09-0
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
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