trans,rel-(1R,2R)-2-(3,4,5-Trifluorophenyl)cyclopropane-1-carboxylic Acid - Names and Identifiers
| Name | trans,rel-(1R,2R)-2-(3,4,5-Trifluorophenyl)cyclopropane-1-carboxylic Acid
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| Synonyms | trans-2-(3,4,5-trifluorophenyl)cyclopropane-1-carboxylic acid
Cyclopropanecarboxylic acid, 2-(3,4,5-trifluorophenyl)-, (1R,2R)-
trans,rel-(1R,2R)-2-(3,4,5-Trifluorophenyl)cyclopropane-1-carboxylic Acid
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| CAS | 2059913-92-5
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trans,rel-(1R,2R)-2-(3,4,5-Trifluorophenyl)cyclopropane-1-carboxylic Acid - Physico-chemical Properties
| Molecular Formula | C10H7F3O2
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| Molar Mass | 216.16 |
| Density | 1.519±0.06 g/cm3(Predicted) |
| Boling Point | 295.5±40.0 °C(Predicted) |
| pKa | 4.51±0.10(Predicted) |
trans,rel-(1R,2R)-2-(3,4,5-Trifluorophenyl)cyclopropane-1-carboxylic Acid - Introduction
trans,rel-(1R,2R)-2-(3,4,5-Trifluorophenyl)cyclopropane-1-carboxylic Acid is a compound with the chemical formula C10H9F3O2.
Nature:
-Appearance: White crystalline solid
-Solubility: Soluble in some organic solvents, such as ethanol, dimethyl sulfoxide and dichloromethane.
-Melting Point: about 140-145 ℃
-This compound has a stereoisomer and the chemical name is (1R,2R)-2-(3,4, 5-trifluorophenyl) cyclopropane -1-carboxylic acid.
Use:
- trans,rel-(1R,2R)-2-(3,4,5-Trifluorophenyl)cyclopropane-1-carboxylic Acid is a reagent commonly used in organic synthesis. It can be used to synthesize compounds with biological activity, such as drugs and pesticides.
-It can also be used as a chiral inducer and a catalyst for chiral chemical reactions.
Method:
Generally, trans,rel-(1R,2R)-2-(3,4,5-Trifluorophenyl)cyclopropane-1-carboxylic Acid can be prepared by the following steps:
1. First, 2-(3,4, 5-trifluorophenyl) Cyclopropane is synthesized by an appropriate compound synthesis procedure. This can be achieved by reaction of the corresponding arylarenes and Cyclopropane Derivatives.
2. Then, under appropriate conditions, 2-(3,4, 5-trifluorophenyl) Cyclopropane is reacted with carboxylic acid compounds to form trans,rel-(1R,2R)-2-(3,4,5-Trifluorophenyl)cyclopropane-1-carboxylic Acid.
Safety Information:
Last Update：2024-04-09 21:01:54